Protein Alignment Ugt37D1 and Ugt1a2

DIOPT Version :9

• Sequence 1: NP_001285989.1
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_038729.1
• Gene: Ugt1a2 / 22236
• MGIID: 3576049
• Length: 533
• Species: Mus musculus
• Alignment Length: 582
• Identity: 158/582 - (27%)
• Similarity: 262/582 - (45%)
• Gaps: 115/582 - (19%)

  Fly    13 LGGLLVALLALQTMPQGTEGANILGVFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSSVPPKVTHK 77
            :.|||:.|.||    ...|||.:|  ......|.::....:::.|..:||...|::|
Mouse    12 ISGLLLLLCAL----PWAEGAKVL--VLPMEGSQWLSMRDVVRELHARGHQTVVLAS-------- 62

  Fly    78 SINHIVVPMSAED-----------------EKVLNDGMAGMVKEKPSIWNTMKSIF--------- 116
               .:.|.:..||                 :::|:|     :::.....:.:|:.|
Mouse    63 ---EVTVHIKGEDFFTLKTYAFPYTKEEYQQEILSD-----IEKTFKTQHFVKAFFETTASIRNF 119

  Fly   117 ------SSLALLIDKQV---------DV-LEDPRFQ-ELYLNKGNKFDVVFVGFFFNTYQVALGA 164
                  |.:|||.:|.:         || |.||.|. ...|.|..:...||:     ...::.|.
Mouse   120 FDLYSNSCIALLHNKMLIQQLNSSFFDVILTDPIFPCGAVLAKYLQIPAVFI-----LRSLSCGI 179

  Fly   165 RF---NCPVIISWSGPPMMMVNEVLGNPELSSVPQM--HISAPPGQPMNFQQRMQNFASTLGFNA 224
            .:   .||                  ||. |.:|.:  .:|    ..|:|.||:||....|....
Mouse   180 EYEATQCP------------------NPS-SYIPNLLTRLS----DHMDFLQRVQNMLYYLVLKY 221

  Fly   225 LNIFLNHKYNKFYDRLWSKDKSMPTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKS 289
            :.......|......|..::.|:   .:...:.|:....|..:.:.| ||.:|.::.||||...:
Mouse   222 ICRLSITPYESLASELLQREVSL---VEVLSHASVWLFRGDFVLDYP-RPIMPNMVFIGGINCVT 282

  Fly   290 KPDPLPEDIQEFLE-KGKHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWED--PKN 351
            | .||.::.:.::. .|:||.::|||||.:  ..|..:....|.:.|..:.|.|:|::..  |.|
Mouse   283 K-KPLSQEFEAYVNASGEHGIVVFSLGSMV--SEIPEKKAMEIAEALGRIPQTVLWRYTGTRPSN 344

  Fly   352 TPGKSANILYKKWLPQDDILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVA 416
            .   :.|.:..|||||:|:|.|||.:.||||:|..|:.|...:||||:.:|:|.||..||.::..
Mouse   345 L---AKNTILVKWLPQNDLLGHPKTRAFITHSGSHGIYEGICNGVPMVMMPLFGDQMDNAKRMET 406

  Fly   417 SGYGLQLPLATLDVDEFKAAIKEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGA 481
            .|.|:.|.:..:..|:.:.|:|.||.|..|.:.:...|.|::|||:.|.:..|:|.|||:||.||
Mouse   407 RGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGA 471

  Fly   482 AHMQSPLVH-MNFIASNNLDIY-IIAALVLYIVFIINKIVWKFVWRKLFGKSNKVSKGKKVK 541
            .|:: |..| :.:...::||:. .:.|:||.:|||:.|.. .:..||.||...:|.|..|.|
Mouse   472 PHLR-PAAHDLTWYQYHSLDVIGFLLAIVLTVVFIVFKCC-AYGCRKCFGGKGRVKKSHKSK 531

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	140/539 (26%)
		UDPGT	45..530	CDD:278624	143/537 (27%)
Ugt1a2	NP_038729.1	UDPGT	28..524	CDD:278624	146/553 (26%)
		Glycosyltransferase_GTB_type	43..>175	CDD:299143	27/152 (18%)
		egt	<261..505	CDD:223071	89/251 (35%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840658
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H86211
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.840