DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37D1 and ugt-55

DIOPT Version :9

Sequence 1:	NP_001285989.1	Gene:	Ugt37D1 / 53511	FlyBaseID:	FBgn0040260	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_506073.2	Gene:	ugt-55 / 188072	WormBaseID:	WBGene00011452	Length:	512	Species:	Caenorhabditis elegans

Alignment Length:	523	Identity:	140/523 - (26%)
Similarity:	222/523 - (42%)	Gaps:	88/523 - (16%)

- Green bases have known domain annotations that are detailed below.

  Fly    44 PSHFIVHMSIMKTLAEKGHNVTVV-----SSVPPKVTHKSINHIV-VPMSAEDEKVLND------ 96
            |||.....:|...|.::||||.||     |.:..|:..|.|..:| |..||...|:|.|
Worm    34 PSHVAFVANIANLLGQRGHNVVVVDNVLRSDISNKLDLKVIEKVVKVETSANVAKLLADQSIPIN 98

  Fly    97 --GMAGMVKEKPSIWNTMKSIF-SSLALLIDKQVDVLEDPRFQELYLNKGNKFDVVFVGFFFNTY 158
              .|....:|:..:...:..|| .....|:.|:..|..:.:..|........||:..:|.|
Worm    99 FWSMRNEPEEQKKVMKQLGIIFLEQCKYLVSKEETVFNELKHLEFDFGIHEVFDICGIGIF---- 159

  Fly   159 QVALGARFNCPVIISWSGPPMMMVNEVLGNPELSSVPQMHISAPPGQPMNFQQRMQNFASTLGFN 223
             ..||.|.:  ||:|.:| ...:|||.||   :||            .:.....:.::.:::.|.
Worm   160 -EKLGIRKS--VILSSTG-MRDIVNEALG---ISS------------QLQDASILSDYGNSIPFY 205

  Fly   224 AL--NIFLNHKYNKFYDRLWSKD-----KSMPTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVIE 281
            .:  |:..:..:..|:: :.||.     ::..:|....|..:|.|.|.|.:::.. ||....|.|
Worm   206 GIRRNLKFHSAWRNFFE-VQSKTLEPLFETTSSFENLLRFSNLMFLNTHELADAH-RPWSRRVHE 268

  Fly   282 IGGIQVKSKPDPLPEDIQEFLEKGKHGAILFSLGSNLKGEHIQPEVVK-TIFKGLSSLKQQV-IW 344
            ||||..|. |.||..:......| .:..||.|.|:... ..:.||..| |:..........: ||
Worm   269 IGGISFKF-PMPLKNEYINLFNK-YNSIILVSFGTTTP-SFLMPEKYKNTLINTFQRFPDFLFIW 330

  Fly   345 KWE--DPKNTPGKSANILYKKWLPQDDILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQ 407
            |:|  |......|..|:::||:|||.|:|...|:||||||.|:..:.|..:.....|..|:|.||
Worm   331 KYEKDDEFTQKNKKGNVVFKKFLPQVDLLESRKIKLFITHGGQNSLLETFHSNTRTLITPLFGDQ 395

  Fly   408 PGNADKLVASGYGLQLPLATLDVDEF-KAAIKEVIENP--------KYAKTLKSFSQLYRDRPLS 463
            ..||...:.:|....|....|..:|. .||||:..|:.        |.:..||:..|...:..|.
Worm   396 HRNAQIALENGLSHVLLKDQLANEELVYAAIKQGTESNKKLDDNLLKLSSNLKNAKQTSENLFLD 460

  Fly   464 PQESVVYWTEYVIRHHGAAHMQSPLVHMNF------IASNNLDIYI--IAALVLYIVFIINKIVW 520
            ..||.  :|:.:          |||   ||      .:|:.:.:|:  ||...|.::.:|  ::.
Worm   461 TVEST--YTDNL----------SPL---NFEFYPKLYSSDQILLYLDSIAMFTLTLLTMI--LIR 508

  Fly   521 KFV 523
            ||:
Worm   509 KFL 511

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	137/510 (27%)
Ugt37D1	NP_001285989.1	UDPGT	45..530	CDD:278624	139/522 (27%)
ugt-55	NP_506073.2	UDPGT	35..>399	CDD:278624	107/391 (27%)
ugt-55	NP_506073.2	Glycosyltransferase_GTB_type	<247..>399	CDD:299143	53/155 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.910