DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37D1 and ugt-59

DIOPT Version :9

Sequence 1:	NP_001285989.1	Gene:	Ugt37D1 / 53511	FlyBaseID:	FBgn0040260	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_501911.1	Gene:	ugt-59 / 187799	WormBaseID:	WBGene00011238	Length:	506	Species:	Caenorhabditis elegans

Alignment Length:	527	Identity:	122/527 - (23%)
Similarity:	207/527 - (39%)	Gaps:	101/527 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    34 NILGVFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSSVPPKVTHKSINHIVVPMSAEDEKVLNDGM 98
            |||....:.|.||...:..:.:.||..||.|||:.:        .::..::..:|.|..||...:
Worm    22 NILFYVPTLSHSHISFNTKLAQLLATSGHQVTVLLA--------QVDDALLIENATDFAVLRKKV 78

  Fly    99 A---GMVKEKPSIWNT----------MKSIFSSLALLIDKQVDVLEDPRFQELYLN--KGNKFDV 148
            .   |.:::  .:|:.          ...||..|..:....|...::..|..|:|:  :..||||
Worm    79 GVPRGHLRQ--VLWSNPGPYEDSSPLNPRIFYKLLKVSGTFVTACQNMAFDHLFLSSLQQQKFDV 141

  Fly   149 VFV------GF-------FFNTYQVALGARFNCPVIISWSGPPMMMVNEVLG-NPELSSVPQM-- 197
            ..|      ||       ..||..::..|.:.          |..   |.|| :...|.||::
Worm   142 GLVEQYDSCGFGIFKSIGIENTVWLSATAIYR----------PQA---EALGVHLPYSYVPELFA 193

  Fly   198 HISAPPGQPMNFQQRMQN--FASTLGFNALNIFLNHKYNKFYDRLWSKDKSMPTFAQAKRNV--- 257
            |.|    ..|:|.|::.|  ......| .|::|:    ..|..|::..::.:...:|...:|
Worm   194 HFS----DKMSFFQKVINILIGQATSF-VLDVFV----QGFQSRIFGFEQGLGAISQETSSVLIN 249

  Fly   258 SLAFCN-----GHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLEKGKHGAILFSLGSN 317
            |:.|.:     .|..|            .||||.|..:...|....|...:..::|.:|.|.|..
Worm   250 SVPFFDYSMPVSHQFS------------NIGGITVDKRDKKLDPYWQSIADSAENGFVLVSFGGI 302

  Fly   318 LKGEHIQPEVVKTIFKGLSSLKQ-QVIWKWEDPKN-TPGKSANILYKKWLPQDDILAHPKLKLFI 380
            .:...:...:.:..:...:.... ..|.|:|...| |.....|::...|:||..::||...|..|
Worm   303 ARTVDMTESMQRIFYDSFARFSHITFIVKYETSSNSTISVPDNVILTPWIPQLPLMAHKNYKTII 367

  Fly   381 THAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFKAAIKEVIENPK 445
            ||.|...:.|...|..||:.:|:|||...|:....:.|..:.|....|.......||..::.|||
Worm   368 THGGWSSILETTMHSKPMILMPLFADHAKNSKVAESKGVAVLLDKMRLSRRRVVHAIYTILTNPK 432

  Fly   446 YAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHG-------AAHMQSPLVHMNFIASNNLDIYI 503
            |.:..:.||:::.|.|: |.|.::.|.   ||...       |.|::......:::   .|...|
Worm   433 YTQNCEKFSRMFSDTPI-PHEELIEWR---IRQAAKPSRKAFAKHLRPKEPDFSYL---KLGFLI 490

  Fly   504 IAALVLY 510
            |.|::||
Worm   491 IPAMILY 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	122/527 (23%)
Ugt37D1	NP_001285989.1	UDPGT	45..530	CDD:278624	118/516 (23%)
ugt-59	NP_501911.1	UDPGT	33..490	CDD:278624	113/507 (22%)
ugt-59	NP_501911.1	Glycosyltransferase_GTB_type	<247..492	CDD:299143	62/263 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.010