DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt37D1 and ugt-41

DIOPT Version :9

Sequence 1:	NP_001285989.1	Gene:	Ugt37D1 / 53511	FlyBaseID:	FBgn0040260	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_504818.2	Gene:	ugt-41 / 184295	WormBaseID:	WBGene00017336	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	548	Identity:	150/548 - (27%)
Similarity:	231/548 - (42%)	Gaps:	78/548 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LLVALLALQTMPQGTEGANILGVFTSHSPSHFIVHMSIMKTLAEKGHNVTV----VSSVPPKVTH 76
            |::.||.|..  ..|.|.|.|.|..:...||......:..:|.|.||||||    :||....:::
Worm     4 LIILLLVLSI--SNTSGFNYLVVSPAFGHSHSTFMGKLADSLTEAGHNVTVLSIIISSKFRNISY 66

  Fly    77 -KSINHIVVPMSAED-----EKVLNDGMAGMVKEKPSIWNTMKSIFSSLALLID----------K 125
             ||...|||..:..:     |.:.||..|....::.::..|:.|....|.:..|          .
Worm    67 TKSTKDIVVVETTTEQDQLTENMENDDFARYWTQEGTMLETIPSYLMFLKMAEDGYKTFRDHALP 131

  Fly   126 QVDVLEDPRFQELYLNKGNKFDVVFV-GFFFNTYQVALGARFNCPVIISWSGPPMMMVN------ 183
            |:|.|::.|.|         :|.||. .|||  ...|:......||.:     |:..:.
Worm   132 QMDYLKNNRPQ---------YDAVFFESFFF--MGKAIQEYLEIPVFL-----PVTSITHDYRFA 180

  Fly   184 EVLGNPELSSVPQMHIS---APPGQPMNFQQRMQNFASTLGFNALNIFLNHKYNKFYDRLWS--K 243
            |::|.|    |...::|   ...|..||||:|:.|..|......|..|.|          |.  :
Worm   181 ELIGEP----VSPSYLSGYFTNFGNIMNFQERLTNTISYYLGQILIAFPN----------WKTLQ 231

  Fly   244 DKSMPTFAQAK-RNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQV---KSKPDPLPEDIQEFLEK 304
            |.|.....::: ......|.|.:...:.| ||.:...||||||.|   |.|.:.:.|.....|:|
Worm   232 DPSKDLLVESEYHRAPYVFINSNPYIDFP-RPLLSKTIEIGGITVDVKKLKSEKVDEKWDNILKK 295

  Fly   305 GKHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQ-QVIWKWEDPKNTPGKSA-NILYKKWLPQ 367
            ..|. :|.|.||..|..::.....:.:.|.:.|.|. ..|||:|..:.:....| ||::.||:||
Worm   296 RPHN-VLISFGSMFKSIYMPDFYKENMVKVMKSFKNVSFIWKYESEETSFANGAENIIFSKWVPQ 359

  Fly   368 DDILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLD-VD 431
            ..:||..:|..|.||.|.|.|.|..|.|.|.|..|:||||..|:..|......:::....|: .:
Worm   360 TALLADSRLSAFFTHGGLGSVNELSYLGKPALLCPLFADQIRNSKMLTRHNGSIEISKFNLENYN 424

  Fly   432 EFKAAIKEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVHMNFIAS 496
            ..::|:..::....|::..:..::....:|..|:|..|...|:..|........|.|..|.|.|.
Worm   425 TLRSALHSILFAESYSENAEKLAKKLEYQPTKPKELFVRHAEFAARFGEQPAQDSNLRTMGFAAY 489

  Fly   497 NNLDIYI----IAALVLYIVFI-INKIV 519
            ..||:..    ...||:::||| |.:||
Worm   490 YLLDVIAFLTSFVLLVIFVVFIMIRQIV 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	140/529 (26%)
Ugt37D1	NP_001285989.1	UDPGT	45..530	CDD:278624	141/519 (27%)
ugt-41	NP_504818.2	UDPGT	22..510	CDD:278624	137/519 (26%)
ugt-41	NP_504818.2	Glycosyltransferase_GTB_type	26..512	CDD:299143	137/517 (26%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.910