DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt37D1 and ugt-9

DIOPT Version :9

Sequence 1:	NP_001285989.1	Gene:	Ugt37D1 / 53511	FlyBaseID:	FBgn0040260	Length:	543	Species:	Drosophila melanogaster
Sequence 2:	NP_504312.1	Gene:	ugt-9 / 178883	WormBaseID:	WBGene00020587	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	564	Identity:	130/564 - (23%)
Similarity:	242/564 - (42%)	Gaps:	77/564 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 LLVALLALQTMPQGTEGANIL---GVFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSSVPPKVTHK 77
            |:::|::.:         |||   .:| .:|.:.|:..::  ..:|:.||||||..  |..:..|
Worm    11 LVISLVSCK---------NILVYNPIF-GYSHAKFVSQLA--NIIADHGHNVTVFQ--PFHIALK 61

  Fly    78 SINHIVVPMSAEDEKVLNDGMAGMVKEK----PSIWNT---MKSIFSSLAL--LIDKQVDVLEDP 133
            :.:.::...:.|......|..|.::|:|    |..|::   ...:.||..:  .:..:.:.....
Worm    62 NTDGLIKNKNIEIINYYPDHYAELLKKKTPTFPDFWDSHLMNNPVLSSFLMPKALGGEFEQTTTQ 126

  Fly   134 RFQ-ELYLN--KGNKFDVVFVGFFFNTYQVA---LGARFNCPVIISWSGPPMMMVNEVLGNPE-L 191
            .|| :..||  |...|||:..    .|:::|   :......|.|...|...:.:::...|.|. |
Worm   127 LFQDQKILNDLKNRNFDVLLA----ETFEIAGFYIADLLEIPSIPLMSAVRLPIIDSAFGQPSIL 187

  Fly   192 SSVPQMHISAPPGQPMNFQQRMQNFASTLGFNALNIFLNHKYNKFYDRLWSKDKSMPTFAQAKRN 256
            ...||.:....|  ...|..|:.:......:|.....|....|.|..:  :....:|.:....:.
Worm   188 GYFPQQYSKVAP--EAGFLDRLNDLYRIFFWNLTTQRLCQFQNDFIQK--AIGHPVPHWRDLVKE 248

  Fly   257 VSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKP----DPLPEDIQEFLEKGKHGAILFSLGSN 317
            ..:...|.:...:..: |....::.:|||.:..:.    ..|.|:.:..|.: :...:..|.||.
Worm   249 SPIYITNSNSYLDFAV-PTTATIVHVGGITIDLEKMRHVAALTEEYENILAE-RESTVFISFGSV 311

  Fly   318 LKG----EHIQPEVVKTIFKGLSSLKQQVIWKWE--DPKNTPGKSANILYKKWLPQDDILAHPKL 376
            ::.    ::.:..::| :||.|..:  ..|||:|  |.|.......|:..|||:||..:||..::
Worm   312 IRSYEMPDNFKAGIIK-MFKSLPDV--TFIWKYEKDDVKFQNRLPKNVHLKKWVPQPSLLADKRV 373

  Fly   377 KLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGL---QLPLATLDVDEFKAAIK 438
            |||:||.|.|...|..|.|.|.|.:|:|.|||.|||.|...|..:   :..||  |.::....::
Worm   374 KLFVTHGGLGSTMEVAYTGKPALMVPIFGDQPNNADMLARHGGAVAYDKFDLA--DGEKLTKTVR 436

  Fly   439 EVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVI---RHHGAAHMQSPLVH-MNFIASNNL 499
            :::.|.||....:...::...:|:.|:.:::...|:.:   :|..    |.|.:: ...||...|
Worm   437 DMVTNSKYEVNAQELLKVLSKQPIDPKLNLMKHLEFAMEFPKHRS----QVPAINRTGLIAHYYL 497

  Fly   500 DIYIIAALVLYIVFIINKIVWKFVWRKLFGKSNKVSKGKKVKKQ 543
            |  :|..|.|..:|.:      ||..|:.....|:...:|||::
Worm   498 D--VIGVLTLASIFGL------FVIFKILNILRKMISLRKVKRE 533

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	120/522 (23%)
Ugt37D1	NP_001285989.1	UDPGT	45..530	CDD:278624	119/517 (23%)
ugt-9	NP_504312.1	egt	20..462	CDD:223071	108/461 (23%)
ugt-9	NP_504312.1	UDPGT	30..532	CDD:278624	123/532 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.910