Protein Alignment Ugt37D1 and Ugt2b37

DIOPT Version :9

• Sequence 1: NP_001285989.1
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_444445.2
• Gene: Ugt2b37 / 112417
• MGIID: 2148239
• Length: 530
• Species: Mus musculus
• Alignment Length: 560
• Identity: 154/560 - (27%)
• Similarity: 257/560 - (45%)
• Gaps: 124/560 - (22%)

  Fly    45 SHFIVHMSIMKTLAEKGHNVTVVSSVPPKVTHKSINHIVVPMSAEDEK-------VLNDGMAGMV 102
            ||::....|:..|.::||.|||:        ..|..:::.|..:...|       |..|.:....
Mouse    34 SHWMNIKIILDELVQRGHEVTVL--------RPSAYYVLDPKKSPGLKFETFPTSVTKDDLENFF 90

  Fly   103 KEKPSIWN-------------TMKSIFSSLA---LLIDKQVDVLED----PRFQELYLNKGNKFD 147
            .:..::|.             .|:::|..|:   |.:.|  ||:.:    .:.||      :|||
Mouse    91 IQLLNVWTYELSRDTCLSYSPLMQNMFDELSGYYLSLCK--DVVSNRQLMTKLQE------SKFD 147

  Fly   148 VVFVGFFFNTYQVALGARFNCPVIISWSGPPMMMVNEVLGNPELSSVPQMHISA----------- 201
            |:.      :..||.|..               ::.|:|..|.|.|   :..:|
Mouse   148 VLL------SDPVAFGGE---------------LIAELLHIPFLYS---LRFTAGYRIEKSSGRF 188

  Fly   202 --PP----------GQPMNFQQRMQNFASTLGFNA-LNIFLNHKYNKFYDRLWSKDKSM-PTFAQ 252
              ||          |..|.|.:|::|....|.|:. ..:..:.|::.||.....:..:: .|..|
Mouse   189 LLPPSYVPVILSGLGGQMTFIERVKNMICMLYFDFWFQMPNDKKWDSFYTEYLGRPTTLAETMGQ 253

  Fly   253 A-----KRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLE-KGKHGAIL 311
            |     :.|..|.|.:          |.:|.|..:||:..| ...|||:|::|::: .|.||.::
Mouse   254 AEMWLIRSNWDLEFPH----------PTLPNVDYVGGLHCK-PAKPLPKDMEEYVQSSGDHGVVV 307

  Fly   312 FSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWEDPKNTPGKSANILYKKWLPQDDILAHPKL 376
            |||||.:  .:|..|.|..|...|:.:.|:|:||: |.|.......|....|||||:|:|.|||.
Mouse   308 FSLGSMV--SNITEEKVNAIAWALAQIPQKVLWKF-DGKTPATLGHNTRVYKWLPQNDLLGHPKT 369

  Fly   377 KLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFKAAIKEVI 441
            |.||||.|...|.||.|||:||:.:|:|.:|..|...:||.|..:.|.:.|:...:...|::|||
Mouse   370 KAFITHGGANSVYEAIYHGIPMIGIPLFGEQHDNIAHMVAKGAAVTLNIRTMSRSDVLNALEEVI 434

  Fly   442 ENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVH-MNFIASNNLDI--YI 503
            |||.|.|.....|.::.|:|:.|.:..|:|.|:|:||..|.|:: ||.| :.:...::||:  ::
Mouse   435 ENPFYKKNAMWLSTIHHDQPMKPLDRAVFWVEFVMRHKNAKHLR-PLGHNLTWYQYHSLDVIGFL 498

  Fly   504 IAALVLYIVFIINKIVWKFVWRKLFGKSNKVSKGKKVKKQ 543
            :|.:...:|..:..::  |::|..      |:|.||:|.:
Mouse   499 LACVAATVVLTVKCLL--FIYRFF------VTKKKKMKNE 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_001285989.1	egt	25..512	CDD:223071	146/527 (28%)
		UDPGT	45..530	CDD:278624	149/545 (27%)
Ugt2b37	NP_444445.2	UDPGT	24..527	CDD:278624	152/555 (27%)
		Glycosyltransferase_GTB_type	42..>174	CDD:299143	34/171 (20%)
		egt	<270..489	CDD:223071	88/223 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167840552
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.840