Protein Alignment Ugt37D1 and Ugt2b34

DIOPT Version :10

• Sequence 1: NP_652627.2
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_705826.1
• Gene: Ugt2b34 / 100727
• MGIID: 2140962
• Length: 532
• Species: Mus musculus
• Alignment Length: 548
• Identity: 155/548 - (28%)
• Similarity: 268/548 - (48%)
• Gaps: 49/548 - (8%)

  Fly    16 LLVALLALQTMPQGTEGANILGVFTSHSPSHFIVHMSIMKTLAEKGHNVTVV---SSVPPKVTHK 77
            ||:.||.|........|..:| |:.... ||::...:|:..|.:|||.|.|:   :|:..:|.:.
Mouse     9 LLLLLLQLSGFFGSGTGGKVL-VWPMEF-SHWLNLKTILDELLKKGHEVMVLRPSASLSYEVDNT 71

  Fly    78 S-INHIVVPMS---AEDEKVLNDGMAGMVKEKPSIWNTMKSIFSSLALLIDKQVDVLEDPRF--- 135
            | |.....|.|   :|.|::..:.:...:.|.|      |..|....|::.:.|.|  |.::
Mouse    72 SAIEFETYPTSYSLSELEEIFWESLKKYIYELP------KQSFWGYFLMLQEMVWV--DSKYFES 128

  Fly   136 --QELYLNK-------GNKFDVVFVGFFFNTYQVALGARFNCPVIISWSGPPMMMVNEVLGNPEL 191
              :::..||       .::|||:....|.....: |......|::.|....|.....:..|...|
Mouse   129 LCKDVVFNKELMTKLQKSRFDVILADPFIPCGDL-LAEVLKIPLVYSLRFFPGSTYEKYSGGLPL 192

  Fly   192 --SSVPQMHISAPPGQPMNFQQRMQNFASTLGFNALNIFLNHKYN-KFYDRLWSKDKSMP-TFAQ 252
              |.||.  :.:.....|.|.:|::|....|.|:    |....:| |.:::|:::....| |.::
Mouse   193 PPSYVPV--VMSELSDRMTFMERVRNVIYMLCFD----FWFQTFNEKNWNQLYTEVLGRPTTLSE 251

  Fly   253 AKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEFLE-KGKHGAILFSLGS 316
            ......:.....:...|.| .|.:|....|||:..: ...|||::|::|:: .|:||.::|||||
Mouse   252 TMAKADIWLIRTYWDLEFP-HPVLPNFDFIGGLHCR-PAKPLPKEIEDFVQSSGEHGVVVFSLGS 314

  Fly   317 NLKGEHIQPEVVKTIFKGLSSLKQQVIWKWEDPKNTPGKSANILYKKWLPQDDILAHPKLKLFIT 381
            .:..  |..|....|..||:.:.|:|:|::|..|.....|...|| ||:||:|:|.|.|.:.|||
Mouse   315 MVGS--ITEERANVIAAGLAQIPQKVLWRFEGKKPETLGSNTRLY-KWIPQNDLLGHSKTRAFIT 376

  Fly   382 HAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDVDEFKAAIKEVIENPKY 446
            |.|..|:.||.|||:|::.:|:|.||..|...|.|.|..::|...|:...:...|:|.|..:|.|
Mouse   377 HGGTNGIYEAIYHGIPVVGIPLFGDQYDNIVHLKAKGAAVRLDFLTMSSTDLHTALKTVTNDPSY 441

  Fly   447 AKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVHMNFIASNNLDIY-IIAALVLY 510
            .:.....|:::.|:|:.|.:..|:|.|:|:||.||.|::.....::::..::||:. .:.|.||.
Mouse   442 KENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLSWVQYHSLDVLGFLLACVLT 506

  Fly   511 IVFIINKIVWKFVWRKLFGKSNKVSKGK 538
            ::||:.|.. .|..:|| .|:.:..||:
Mouse   507 VMFILKKCC-LFCCQKL-TKAGRKKKGE 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_652627.2	GT1_Gtf-like	33..471	CDD:340817	127/461 (28%)
Ugt2b34	NP_705826.1	UDPGT	27..529	CDD:278624	147/525 (28%)