Protein Alignment Ugt37D1 and ugt2b3

DIOPT Version :10

• Sequence 1: NP_652627.2
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001170812.2
• Gene: ugt2b3 / 100384898
• ZFINID: ZDB-GENE-100402-2
• Length: 527
• Species: Danio rerio
• Alignment Length: 580
• Identity: 153/580 - (26%)
• Similarity: 259/580 - (44%)
• Gaps: 115/580 - (19%)

  Fly    16 LLVALLALQTMPQGTEGANILGVFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSS-----VPPKVT 75
            |:|..|:|.|:....:..|||...|  ..||:|....::.||.::||||||:..     :..|.:
Zfish     3 LVVCFLSLLTVFSAGQCGNILVWHT--EGSHWINLKIVLDTLLDRGHNVTVLMPDGALFMKAKES 65

  Fly    76 HK-SINHIVVPMSAED-----EKVLNDGMAGMVKEKPSIWNTMKSIFSSLALLIDKQVD------ 128
            .: |..:..|..||:|     :::|:..:..|  |:.::.......|.    |..:..|
Zfish    66 DRFSYQNFSVSTSAQDMQDFLDELLHFSVFEM--EQLNLLQIQMKFFD----LGSRHQDMGLSYC 124

  Fly   129 --VLEDPRFQELYLNKGNKFDVVFVGFFFNTYQVALGARFNCPVIISWSGPPMMMVNEVLGNPEL 191
              :|:.|...:..  |..||||:.                         ..||...::::.  |:
Zfish   125 DGILKSPELMDKL--KTGKFDVLL-------------------------SDPMYPCSDIVA--EV 160

  Fly   192 SSVPQM----------------HISAPPG----------QPMNFQQRMQNFASTLGFNALNIFLN 230
            .:||.:                .|.|||.          ..|:|.:|:.|....|..:..:|...
Zfish   161 LNVPLVFTLRFSIAHTMERICGQIPAPPSYVPGAMSKLTDKMSFTERIFNTLFYLSMDTFSIIAW 225

  Fly   231 HKYNKFYDRLWSKDKSMPTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLP 295
            .|::.:|...:.:..|   :.:......:.....:...|.| ||.||....|||:.. :...|||
Zfish   226 KKFDNYYTEYFGRPTS---YCEMMGRADIWLIRTYWDFEFP-RPFVPNFKYIGGLHC-TPAKPLP 285

  Fly   296 EDIQEFLE-KGKHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWEDPK-NTPGKSAN 358
            :|::||:: .|..|.::|:|||.:  :.:..|:...|...|:.:.|:|:|::...| :|.|::..
Zfish   286 KDMEEFVQSSGDDGIVVFTLGSMI--DKVPKEMSNRIASALAQIPQKVLWRYGGEKPDTLGENTR 348

  Fly   359 ILYKKWLPQDDILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQL 423
            |.  ||:||:|:|.|||.:.||||.|..|:.||.||||||:.:|:|.|||.|...:...|
Zfish   349 IY--KWMPQNDLLGHPKTRAFITHGGTNGIYEAIYHGVPMVGIPLFGDQPDNMVHMTTRG----- 406

  Fly   424 PLATLDVDEFKA--------AIKEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHG 480
              |.:.||..|:        .:..||.:|.|.:.....|:::.|||:.|.:..|:|.|:|:|:.|
Zfish   407 --AAVVVDSIKSMQPQELVDKLNTVINDPSYKENAMRLSRIHHDRPMKPLDESVFWIEFVMRNKG 469

  Fly   481 AAHMQSPLVHMNFIASNNLDIY----IIAALVLYIVFIINKIVWKFVWRKLFGKSNKVSK 536
            |.|::....::.:...:.||::    .:..|||||.|.:.|.   |:.|..|....|..|
Zfish   470 AKHLRVEAHNLTWYQYHCLDVFAFLTTVLTLVLYICFKMAKF---FIMRCCFRSKRKSKK 526

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_652627.2	GT1_Gtf-like	33..471	CDD:340817	127/492 (26%)
ugt2b3	NP_001170812.2	UDPGT	20..523	CDD:278624	146/558 (26%)