Protein Alignment Ugt37D1 and ugt1a6

DIOPT Version :10

• Sequence 1: NP_652627.2
• Gene: Ugt37D1 / 53511
• FlyBaseID: FBgn0040260
• Length: 543
• Species: Drosophila melanogaster
• Sequence 2: NP_001107366.1
• Gene: ugt1a6 / 100135191
• XenbaseID: XB-GENE-5793241
• Length: 531
• Species: Xenopus tropicalis
• Alignment Length: 541
• Identity: 152/541 - (28%)
• Similarity: 253/541 - (46%)
• Gaps: 92/541 - (17%)

  Fly     9 IGCSLGGLLVALLALQTMPQGTEGANILGVFTSHSPSHFIVHMSIMKTLAEKGHNVTVVSSVPP- 72
            :||:.||.|:      .:||  :|            ||::....::..||::||.:.|  ::|.
 Frog    22 LGCADGGRLL------VVPQ--DG------------SHWLSMRVLVDRLAQRGHYIVV--AIPEV 64

  Fly    73 KVTHKSI-NHIVVPMSAEDEK-VLNDGMAGM---------VKEKPSIW-----NTMKSIFSSLAL 121
            .:..|.: |:.|...|:...| ||.:.|..|         :.||.:.|     |..:.:.|:...
 Frog    65 NMLFKDLDNYKVKTFSSPYSKDVLENRMRRMNQEIFVDRILTEKITFWYESMSNATQWVVSACQH 129

  Fly   122 LIDKQVDVLEDPRFQELYLNKGNKFDVVFVGFFFNTYQVALGARFNCPVIISWSGPPMMMVNEVL 186
            .:.....:.|        |.| ..||.:.....|...:: :....:.|.:       ..|...:.
 Frog   130 FLQNSTLIRE--------LEK-EHFDAMLTDSVFPCGEI-VAEHLSIPSV-------SFMRGTIF 177

  Fly   187 GNPELSSVPQMHISAPPG----------QPMNFQQRMQNFASTLGFNALNIFLNHKYNKFY---- 237
            |..:::|    ...:||.          ..|:|.||::||.    .::|...:.|.:...|
 Frog   178 GMDQIAS----QTPSPPSYVPRMFTVYTDNMSFSQRVKNFL----IHSLEHIVCHIFYYPYAQMA 234

  Fly   238 -DRLWSKDKSMPTFAQAKRNVSLAFCNGHGISEGPIRPNVPGVIEIGGIQVKSKPDPLPEDIQEF 301
             |.|..:..:|..|::    .|:.......:.|.| ||.:|.||.||||.. :|...||::.::.
 Frog   235 SDFLKKEVTAMSLFSR----TSIWLMRYDFVFEFP-RPIMPNVILIGGINC-AKQKALPQEFEKL 293

  Fly   302 LE-KGKHGAILFSLGSNLKGEHIQPEVVKTIFKGLSSLKQQVIWKWEDPKNTPGKSANILYKKWL 365
            :: .|:||.::||.||.:  ..|...:...|.:.|..:.|:|.|::.. |..|....|....|||
 Frog   294 VKSSGEHGFVVFSFGSMV--SEIPMNIAMDIAEALRYIPQKVFWRYTG-KAPPNLGDNTHLVKWL 355

  Fly   366 PQDDILAHPKLKLFITHAGKGGVAEAQYHGVPMLALPVFADQPGNADKLVASGYGLQLPLATLDV 430
            ||:|:|||||.:.||||||..||.|...:.|||:.||:..||..||.::.:.|.||.|.:..|..
 Frog   356 PQNDLLAHPKARAFITHAGSHGVYEGICNAVPMVMLPLIGDQMDNAKRIESRGAGLILNVQNLIP 420

  Fly   431 DEFKAAIKEVIENPKYAKTLKSFSQLYRDRPLSPQESVVYWTEYVIRHHGAAHMQSPLVH-MNFI 494
            |:...|:..||:||.|.:.::..|.|:||||:.|.:..|:|.|:|::|.||.|:: |..| :|:|
 Frog   421 DDLSNAVMAVIDNPSYKENIQRLSSLHRDRPVQPLDLAVHWVEFVMKHKGAPHLR-PAAHDLNWI 484

  Fly   495 ASNNLDIY-IIAALVLYIVFI 514
            ...:||:. .:.|::|..:||
 Frog   485 QYQSLDVMAFLLAVLLTTLFI 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt37D1	NP_652627.2	GT1_Gtf-like	33..471	CDD:340817	127/470 (27%)
ugt1a6	NP_001107366.1	UDPGT	28..527	CDD:278624	149/535 (28%)