Protein Alignment Ugt302C1 and UGT2A3

DIOPT Version :9

• Sequence 1: NP_652626.1
• Gene: Ugt302C1 / 53510
• FlyBaseID: FBgn0040259
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: XP_011530549.1
• Gene: UGT2A3 / 79799
• HGNCID: 28528
• Length: 533
• Species: Homo sapiens
• Alignment Length: 579
• Identity: 164/579 - (28%)
• Similarity: 267/579 - (46%)
• Gaps: 117/579 - (20%)

  Fly    10 FLALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTII-----SPFELKKPIK 69
            ||.|.||| :.|  .:...|::.....||:.....:.:.|...||:||::     |..:.:||
Human    10 FLLLQLFC-VGC--GFCGKVLVWPCDMSHWLNVKVILEELIVRGHEVTVLTHSKPSLIDYRKP-- 69

  Fly    70 NIKDVPAKSILTSMQGRIANLLQSSKE-------------PII---KQIINFHEMGIEI--TELL 116
                       ::::..:.::.|...|             |.:   :.:|..::..:||  |..:
Human    70 -----------SALKFEVVHMPQDRTEENEIFVDLALNVLPGLSTWQSVIKLNDFFVEIRGTLKM 123

  Fly   117 LKEPSVIE--LMKSNQ--TFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGA------------I 165
            :.|..:..  |||..|  .:|.::.:                |:|..|...|            |
Human   124 MCESFIYNQTLMKKLQETNYDVMLID----------------PVIPCGDLMAELLAVPFVLTLRI 172

  Fly   166 SWNTDLVGS----PSPPSYVPSALLKFSDRMSLVERVGNQAFLT--------YEYIFLNYFY--- 215
            |...::..|    |:|.||||..:...:|||:.:|||.|.....        |:|.|...||
Human   173 SVGGNMERSCGKLPAPLSYVPVPMTGLTDRMTFLERVKNSMLSVLFHFWIQDYDYHFWEEFYSKA 237

  Fly   216 LPRQEVLYRKYFPNNKQDFYDMRKNTALVLLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPK- 279
            |.|...|....   .|.:.:         |:..:....||:||.||...|||:|. :..:.|||
Human   238 LGRPTTLCETV---GKAEIW---------LIRTYWDFEFPQPYQPNFEFVGGLHC-KPAKALPKI 289

  Fly   280 -----DILEFIEGA-EHGVIYFSMGSNLKSKTLPLEKRQALIDTFAQLKQRVLWKFEDTDLPGKP 338
                 ::..|::.: |.|::.||:||..::.|  .||...:....||:.|:|||:::........
Human   290 NFYLQEMENFVQSSGEDGIVVFSLGSLFQNVT--EEKANIIASALAQIPQKVLWRYKGKKPSTLG 352

  Fly   339 ANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGV 403
            ||..:.||.||:|:|.|....|||||||:....|:|||..|.||:||||||..|:|..:..|..|
Human   353 ANTRLYDWIPQNDLLGHPKTKAFITHGGMNGIYEAIYHGVPMVGVPIFGDQLDNIAHMKAKGAAV 417

  Fly   404 TVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRS 468
            .::::.::|..||.|::.:|.:....:....:|..:.||...||:|||:|:|.|.||||||:|||
Human   418 EINFKTMTSEDLLRALRTVITDSSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRS 482

  Fly   469 ASQDLNFIQYHNLDAMLILYGGIIFVLYCIFLLIRLVWRLLQELFIKKDTSKPKQKAKR 527
            |:.||.:.|::::|.       |.|:|.|:...|.|..:..  ||..:..:|.::..||
Human   483 AAHDLTWFQHYSIDV-------IGFLLACVATAIFLFTKCF--LFSCQKFNKTRKIEKR 532

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	120/386 (31%)
UGT2A3	XP_011530549.1	UDPGT	24..528	CDD:278624	155/556 (28%)
		egt	<267..498	CDD:223071	90/240 (38%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150236
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm8543
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.690