DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt1b7

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_001166240.1	Gene:	ugt1b7 / 795261	ZFINID:	ZDB-GENE-080227-15	Length:	542	Species:	Danio rerio

Alignment Length:	510	Identity:	164/510 - (32%)
Similarity:	251/510 - (49%)	Gaps:	70/510 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    37 SHYHVGSALAKGLAAAGHQVTIISP--FELKKPIKN--IKDVP---AKSILTSMQGRIANLLQSS 94
            ||:....|||:.:...||:||::.|  ..|..|.|:  .:..|   .|..|..:|.|.|.:::|.
Zfish    52 SHWTGVKALAEEMGRRGHKVTVVIPEVSVLLGPGKHYVTRTFPVLYGKQQLDELQARNAQVMESK 116

  Fly    95 KEPIIKQI----------INFHEMGIEITELLLKEPSVIELMKSNQTFDAVISEVFLNEAHFGFA 149
            :.|::::|          :|......|  .|||.:..|..|.|.|  ||||::
Zfish   117 QLPLMEKISTRFSNMRKFVNLQRATAE--SLLLNQELVDFLRKQN--FDAVLT------------ 165

  Fly   150 EHFKAPLIGLGTFGAISWNTDL-----------------VGSPSPPSYVPSALLKFSDRMSLVER 197
                :|.:..|..  :::|..|                 ...|:||||:|......|||||..:|
Zfish   166 ----SPAVPTGAI--LAYNLSLPAVYMLRGLPCGLDSVATACPNPPSYIPRFFTHSSDRMSFGQR 224

  Fly   198 VGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTALVLLNQHVSLSFPRPYSPNM 262
            |.|......|.:.....|...::|..|  |........::..:.||.||....:|.||:|..|||
Zfish   225 VLNVLVSMLEPLLCRLIYWTTEDVASR--FMQRDVSVTEVLSSGALWLLRYDFTLEFPKPLMPNM 287

  Fly   263 IEVGGMHINRKRQPLPKDILEFIEGA-EHGVIYFSMGSNLKSKTLPLEKRQALIDTFAQLKQRVL 326
            :.:||::. ..|.||.|::.||:.|: |||::.||:||.:.|  :|.||.......|:.:.||||
Zfish   288 VLIGGINC-AIRHPLTKEVEEFVNGSGEHGIVVFSLGSLVSS--MPKEKADIFFKAFSMIPQRVL 349

  Fly   327 WKFEDTDLPGK-PANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPIFGDQF 390
            |::.. ::|.. |.||.:..|.||:|:|.|....|||||||.....|.|.|..|.|.:|:||||.
Zfish   350 WRYTG-EIPNNVPENVKLMKWLPQNDLLGHPKARAFITHGGTHGIYEGICHGVPMVMLPLFGDQA 413

  Fly   391 LNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLERAVYWVE 455
            .|:.|....|.||.:...:::...||.|:..:|||....|:::.:|..:.|:...||:.||:|.|
Zfish   414 DNVHRVATRGVGVILSIHDITVETLLDALNSVINNSSYKQKMQKLSAIHNDRPIQPLDLAVFWTE 478

  Fly   456 HVSRHKGAKYLRSASQDLNFIQYHNLDA---MLILYGGIIFVLYCIFLLIRLVWR 507
            .|.|||||.:||.|:.:||::|||:||.   ||::   ::.|...:.....|.||
Zfish   479 FVMRHKGADHLRPAAHELNWLQYHSLDVIGFMLLI---VLIVTLAMLKCCSLCWR 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	122/367 (33%)
ugt1b7	NP_001166240.1	UDPGT	42..538	CDD:278624	164/510 (32%)
ugt1b7	NP_001166240.1	egt	<282..521	CDD:223071	96/245 (39%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584737
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	2	1.830