Protein Alignment Ugt302C1 and UGT8

DIOPT Version :9

• Sequence 1: NP_652626.1
• Gene: Ugt302C1 / 53510
• FlyBaseID: FBgn0040259
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: NP_001121646.2
• Gene: UGT8 / 7368
• HGNCID: 12555
• Length: 541
• Species: Homo sapiens
• Alignment Length: 524
• Identity: 150/524 - (28%)
• Similarity: 266/524 - (50%)
• Gaps: 36/524 - (6%)

  Fly    13 LLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPIKNIKDVPAK 77
            :||:..:....|...::|......||.::...||..|...||....:        :...:|: |.
Human     9 ILLWSAVGIAKAAKIIIVPPIMFESHMYIFKTLASALHERGHHTVFL--------LSEGRDI-AP 64

  Fly    78 SILTSMQGRIANLLQSSK-----EPIIKQIINFHEMGIEITELLLKEPSVIELMKSN-------- 129
            |...|:| |...:..|:.     :..::.|.:.....||:.::|.......:||..|
Human    65 SNHYSLQ-RYPGIFNSTTSDAFLQSKMRNIFSGRLTAIELFDILDHYTKNCDLMVGNHALIQGLK 128

  Fly   130 -QTFDAVISEVFLNEAHFGFAEHFKAPLIGL--GTFGAISWNTDLVGSPSPPSYVPSALLKFSDR 191
             :.||.::  |..|:. .||.   .|.|:|:  ..|....|....||:|:|.:|||......:||
Human   129 KEKFDLLL--VDPNDM-CGFV---IAHLLGVKYAVFSTGLWYPAEVGAPAPLAYVPEFNSLLTDR 187

  Fly   192 MSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTALVLLNQHVSLSFPR 256
            |:|::|:.|........:.:::..||:.|.:.:||....::..||:...::|.:|...|:|.|||
Human   188 MNLLQRMKNTGVYLISRLGVSFLVLPKYERIMQKYNLLPEKSMYDLVHGSSLWMLCTDVALEFPR 252

  Fly   257 PYSPNMIEVGGMHINRKRQPLPKDILEFIEGA-EHGVIYFSMGSNLKSKTLPLEKRQALIDTFAQ 320
            |..||::.|||: :.:...|||:|:..::.|| |||.:..|.|:.:|..:..:..:  |.....:
Human   253 PTLPNVVYVGGI-LTKPASPLPEDLQRWVNGANEHGFVLVSFGAGVKYLSEDIANK--LAGALGR 314

  Fly   321 LKQRVLWKFEDTDLPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPI 385
            |.|:|:|:|..........|..:.:|.||:|:|.|..:.||::||||.|..|:|||..|.||||:
Human   315 LPQKVIWRFSGPKPKNLGNNTKLIEWLPQNDLLGHSKIKAFLSHGGLNSIFETIYHGVPVVGIPL 379

  Fly   386 FGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLERA 450
            |||.:..|.|.:..|.|:.:.::.::..:|..|:.|:||||...||.:.:|:.::||...|:.|.
Human   380 FGDHYDTMTRVQAKGMGILLEWKTVTEKELYEALVKVINNPSYRQRAQKLSEIHKDQPGHPVNRT 444

  Fly   451 VYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCIFLLIRLVWRLLQELFIK 515
            :||::::.||.||.:||:|...::|.||..||...:|..|...:.:.:..:.:.::|.::.|:.:
Human   445 IYWIDYIIRHNGAHHLRAAVHQISFCQYFLLDIAFVLLLGAALLYFLLSWVTKFIYRKIKSLWSR 509

  Fly   516 KDTS 519
            ...|
Human   510 NKHS 513

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	115/360 (32%)
UGT8	NP_001121646.2	Glycosyltransferase_GTB-type	21..502	CDD:415824	144/499 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150677
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0.678979	Normalized mean entropy	S5661
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm8543
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.690