Protein Alignment Ugt302C1 and UGT2B17

DIOPT Version :10

• Sequence 1: NP_652626.1
• Gene: Ugt302C1 / 53510
• FlyBaseID: FBgn0040259
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: NP_001068.1
• Gene: UGT2B17 / 7367
• HGNCID: 12547
• Length: 530
• Species: Homo sapiens
• Alignment Length: 550
• Identity: 163/550 - (29%)
• Similarity: 272/550 - (49%)
• Gaps: 59/550 - (10%)

  Fly    10 FLALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPIKNIKDV 74
            ||.:.|.|..|..|....||  .....||:.....:.:.|...||:|.:::      ...:|...
Human     9 FLLMQLSCYFSSGSCGKVLV--WPTEYSHWINMKTILEELVQRGHEVIVLT------SSASILVN 65

  Fly    75 PAKSILTSMQGRIANLLQSSKEPIIKQIIN-----------------FHEMGIEITELLLK--EP 120
            .:||....::....:|.::..|....::.:                 ..|:..|.::..:|  |.
Human    66 ASKSSAIKLEVYPTSLTKNDLEDFFMKMFDRWTYSISKNTFWSYFSQLQELCWEYSDYNIKLCED 130

  Fly   121 SVI--ELMKSNQ--TFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGSP--SPPS 179
            :|:  :||:..|  .||.::::. :|......||....|.:....| ::.:..:..|..  .|||
Human   131 AVLNKKLMRKLQESKFDVLLADA-VNPCGELLAELLNIPFLYSLRF-SVGYTVEKNGGGFLFPPS 193

  Fly   180 YVPSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTALV 244
            |||..:.:.||:|..:||:.|..::.|...:...:.|.:.:..|.:........|..|.| ..:.
Human   194 YVPVVMSELSDQMIFMERIKNMIYMLYFDFWFQAYDLKKWDQFYSEVLGRPTTLFETMGK-AEMW 257

  Fly   245 LLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGA-EHGVIYFSMGSNLKSKTLPL 308
            |:..:....||||:.||:..|||:|. :..:||||::.||::.: |:|::.||:||.:.:  :..
Human   258 LIRTYWDFEFPRPFLPNVDFVGGLHC-KPAKPLPKEMEEFVQSSGENGIVVFSLGSMISN--MSE 319

  Fly   309 EKRQALIDTFAQLKQRVLWKFEDTDLPGKPANVFISD-----WFPQDDILAHDNVLAFITHGGLL 368
            |....:....||:.|:|||:|:     ||..|...|:     |.||:|:|.|....|||||||..
Human   320 ESANMIASALAQIPQKVLWRFD-----GKKPNTLGSNTRLYKWLPQNDLLGHPKTKAFITHGGTN 379

  Fly   369 STTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVR 433
            ...|:|||..|.||||:|.||..|:|..:..|..::|....:||..||.|::.:||:|...:.:.
Human   380 GIYEAIYHGIPMVGIPLFADQHDNIAHMKAKGAALSVDIRTMSSRDLLNALKSVINDPIYKENIM 444

  Fly   434 DMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCI 498
            .:|..:.||...||:|||:|:|.|.||||||:||.|:.:|.:||||:||.       |.|:|.|:
Human   445 KLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHNLTWIQYHSLDV-------IAFLLACV 502

  Fly   499 FLLIRLVWRLLQELFIKKDTSKPKQKAKRN 528
            ..:|.::.:..  ||..:..:|..:|.||:
Human   503 ATMIFMITKCC--LFCFRKLAKTGKKKKRD 530

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	Glycosyltransferase_GTB-type	<185..507	CDD:471961	116/327 (35%)
UGT2B17	NP_001068.1	UDPGT	24..518	CDD:278624	153/521 (29%)