Protein Alignment Ugt302C1 and UGT2B7

DIOPT Version :9

• Sequence 1: NP_652626.1
• Gene: Ugt302C1 / 53510
• FlyBaseID: FBgn0040259
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: NP_001065.2
• Gene: UGT2B7 / 7364
• HGNCID: 12554
• Length: 529
• Species: Homo sapiens
• Alignment Length: 547
• Identity: 165/547 - (30%)
• Similarity: 251/547 - (45%)
• Gaps: 90/547 - (16%)

  Fly    13 LLLFCLLSCVSAYNYLVVLHTAAR-SHYHVGSALAKGLAAAGHQVTIIS---------------- 60
            :||..|..|.|:.|...||..||. ||:.....:...|...||:||:::
Human     9 ILLIQLSFCFSSGNCGKVLVWAAEYSHWMNIKTILDELIQRGHEVTVLASSASILFDPNNSSALK 73

  Fly    61 ----PFELKK---------PIKNIKDVPAKSILTSMQGRIANLLQSSKEPIIKQIINFHEMGIEI 112
                |..|.|         .||...|:|..:.          .|..|:...|..|..      :|
Human    74 IEIYPTSLTKTELENFIMQQIKRWSDLPKDTF----------WLYFSQVQEIMSIFG------DI 122

  Fly   113 TELLLKEPSVIELMKSNQTFDAVISE----VFLNEAHFG----FAEHFKAPLI-GLGTFGAISWN 168
            |....|:      :.||:.|...:.|    |...:|.|.    .||.|..|.: .|......::.
Human   123 TRKFCKD------VVSNKKFMKKVQESRFDVIFADAIFPCSELLAELFNIPFVYSLSFSPGYTFE 181

  Fly   169 TDLVGSPSPPSYVPSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPN---- 229
            ....|...||||||..:.:.:|:|:.:|||.|..::.|...:...|.:.:.:..|.:....
Human   182 KHSGGFIFPPSYVPVVMSELTDQMTFMERVKNMIYVLYFDFWFEIFDMKKWDQFYSEVLGRPTTL 246

  Fly   230 ----NKQDFYDMRKNTALVLLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGA-E 289
                .|.|.:         |:....:..||.|..||:..|||:|. :..:||||::.:|::.: |
Human   247 SETMGKADVW---------LIRNSWNFQFPYPLLPNVDFVGGLHC-KPAKPLPKEMEDFVQSSGE 301

  Fly   290 HGVIYFSMGSNLKSKTLPLEKRQALIDTFAQLKQRVLWKFEDTDLPGKPANVFISDWFPQDDILA 354
            :||:.||:||.:.:.|  .|:...:....||:.|:|||:|:.........|..:..|.||:|:|.
Human   302 NGVVVFSLGSMVSNMT--EERANVIASALAQIPQKVLWRFDGNKPDTLGLNTRLYKWIPQNDLLG 364

  Fly   355 HDNVLAFITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAI 419
            |....|||||||.....|:|||..|.||||:|.||..|:|..:..|..|.|.:..:||..||.|:
Human   365 HPKTRAFITHGGANGIYEAIYHGIPMVGIPLFADQPDNIAHMKARGAAVRVDFNTMSSTDLLNAL 429

  Fly   420 QKIINNPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDA- 483
            :::||:|...:.|..:|....||...||:|||:|:|.|.||||||:||.|:.||.:.|||:||.
Human   430 KRVINDPSYKENVMKLSRIQHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYHSLDVI 494

  Fly   484 --MLILYGGIIFV-----LYCIFLLIR 503
              :|:....:||:     |:|.:...|
Human   495 GFLLVCVATVIFIVTKCCLFCFWKFAR 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	119/366 (33%)
UGT2B7	NP_001065.2	UDPGT	24..525	CDD:278624	159/532 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150447
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm8543
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.690