Protein Alignment Ugt302C1 and UGT2B4

DIOPT Version :9

• Sequence 1: NP_652626.1
• Gene: Ugt302C1 / 53510
• FlyBaseID: FBgn0040259
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: NP_066962.2
• Gene: UGT2B4 / 7363
• HGNCID: 12553
• Length: 528
• Species: Homo sapiens
• Alignment Length: 573
• Identity: 170/573 - (29%)
• Similarity: 269/573 - (46%)
• Gaps: 103/573 - (17%)

  Fly     8 TGFLALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTII-----------SP 61
            :..|.:.|.|..|..|....||  .....||:.....:...|...||:||::           ||
Human     7 SALLLIQLSCYFSSGSCGKVLV--WPTEFSHWMNIKTILDELVQRGHEVTVLASSASISFDPNSP 69

  Fly    62 FELKKPIKNIKDVPAKSILTSMQGRIANLLQSSKEPIIKQII---------NFHEMGIEITELLL 117
            ..||..:..:                 :|.::..|.||||::         .|.....::.|::.
Human    70 STLKFEVYPV-----------------SLTKTEFEDIIKQLVKRWAELPKDTFWSYFSQVQEIMW 117

  Fly   118 KEPSVI-----------ELMKSNQ--TFDAVISE-VFLNEAHFG--FAEHFKAPLIGLGTFG--- 163
            ....::           :|||..|  .||.|::: ||    .||  .||..|.|.:....|.
Human   118 TFNDILRKFCKDIVSNKKLMKKLQESRFDVVLADAVF----PFGELLAELLKIPFVYSLRFSPGY 178

  Fly   164 AISWNTDLVGSPSPPSYVPSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYF- 227
            ||..::.  |...||||||..:.:.||:|:.:|||.|..::.|...:...|.:.:.:..|.:..
Human   179 AIEKHSG--GLLFPPSYVPVVMSELSDQMTFIERVKNMIYVLYFEFWFQIFDMKKWDQFYSEVLG 241

  Fly   228 -PNN------KQDFYDMRKNTALVLLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFI 285
             |..      |.|.:         |:..:....||.|..||:..|||:|. :..:||||::.||:
Human   242 RPTTLSETMAKADIW---------LIRNYWDFQFPHPLLPNVEFVGGLHC-KPAKPLPKEMEEFV 296

  Fly   286 EGA-EHGVIYFSMGSNLKSKTLPLEKRQALIDTFAQLKQRVLWKFEDTDLPGKPANVFISDWFPQ 349
            :.: |:||:.||:||.:.:.:  .|:...:....|::.|:|||:|:.........|..:..|.||
Human   297 QSSGENGVVVFSLGSMVSNTS--EERANVIASALAKIPQKVLWRFDGNKPDTLGLNTRLYKWIPQ 359

  Fly   350 DDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAK 414
            :|:|.|....|||||||.....|:|||..|.||:|:|.||..|:|..:..|..|::.:..:||..
Human   360 NDLLGHPKTRAFITHGGANGIYEAIYHGIPMVGVPLFADQPDNIAHMKAKGAAVSLDFHTMSSTD 424

  Fly   415 LLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYH 479
            ||.|::.:||:|...:....:|..:.||...||:|||:|:|.|.||||||:||.|:.||.:.|||
Human   425 LLNALKTVINDPLYKENAMKLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYH 489

  Fly   480 NLDA---MLILYGGIIFVL-YCIFLLIRLVWRLLQELFIKKDTSKPKQKAKRN 528
            :||.   :|.....:||:: .|:|    .||:.::       |.|   |.||:
Human   490 SLDVTGFLLACVATVIFIITKCLF----CVWKFVR-------TGK---KGKRD 528

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	122/376 (32%)
UGT2B4	NP_066962.2	egt	8..512	CDD:223071	161/540 (30%)
		UDPGT	24..524	CDD:278624	162/550 (29%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150448
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm8543
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.690