Protein Alignment Ugt302C1 and Ugt1a8

DIOPT Version :10

• Sequence 1: NP_652626.1
• Gene: Ugt302C1 / 53510
• FlyBaseID: FBgn0040259
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: NP_001365304.1
• Gene: Ugt1a8 / 613123
• MGIID: 3576090
• Length: 530
• Species: Mus musculus
• Alignment Length: 523
• Identity: 154/523 - (29%)
• Similarity: 243/523 - (46%)
• Gaps: 67/523 - (12%)

  Fly    14 LLFCLL---SCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPIKNIKDVP 75
            |..|||   ....|...|||  ....||:.....:.:.|:..||:|.::.| |:...:...::..
Mouse    12 LRVCLLLAFGLAQAGRLLVV--PMDGSHWFSMKMIVEKLSHRGHEVVVVIP-EVSWHLGKSQNFT 73

  Fly    76 AKSILTSMQ---------------------GRIANLLQSSKEPIIKQIINFHEMGIEITELLLKE 119
            .|:...|..                     |..:.|..|.|        .|.::.......|..:
Mouse    74 VKTYSVSYTLEDLSHHFNFFAHKQWENREVGMFSLLKHSGK--------GFFQVLFSHCRSLFND 130

  Fly   120 PSVIELMKSNQTFDAVISEVFLNEAHFGFAEHFKAPLIGL--GTF------GAISWNTDLVGSPS 176
            ..::|.:| .::||||..:.| :......|::|..|.:..  |.|      ||        ..||
Mouse   131 KKLVEYLK-QRSFDAVFLDPF-DVCGLTIAKYFSLPSVVFSGGIFCHYLDEGA--------QCPS 185

  Fly   177 PPSYVPSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLP----RQEVLYRKYFPNNKQDFYDM 237
            ||||||..|.||:|.|:..|||.|......|..|..||:..    ..|||..   |....|.:
Mouse   186 PPSYVPRILSKFADTMTFKERVWNYFSYMKERAFCPYFFKTAIEIASEVLQT---PVTMTDLF-- 245

  Fly   238 RKNTALVLLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGA-EHGVIYFSMGSNL 301
             .:.::.:......|.||||..|||:.:||::.: ..:||.|:...::..: |||::.||:||.:
Mouse   246 -SSVSIWMFRTDFVLEFPRPVMPNMVYIGGINCH-PGKPLSKEFEAYVNASGEHGIVVFSLGSMV 308

  Fly   302 KSKTLPLEKRQALIDTFAQLKQRVLWKFEDTDLPGKPANVFISDWFPQDDILAHDNVLAFITHGG 366
            ..  :|.:|...:.:...::.|.|||::..|.......|..:..|.||:|:|.|....|||||.|
Mouse   309 SE--IPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKTRAFITHSG 371

  Fly   367 LLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQR 431
            .....|.|.:..|.|.:|:||||..|..|.|..|.|||::..|:::..|..|::.:|||....:.
Mouse   372 SHGIYEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKEN 436

  Fly   432 VRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLY 496
            :..:|..::|:...||:.||:|||:|.|||||.:||.|:.||.:.|||:||.:..|...::.|::
Mouse   437 IMRLSSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFLLAIVLTVVF 501

  Fly   497 CIF 499
            .:|
Mouse   502 IVF 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	Glycosyltransferase_GTB-type	<185..507	CDD:471961	108/320 (34%)
Ugt1a8	NP_001365304.1	UDPGT	26..521	CDD:278624	149/509 (29%)