Protein Alignment Ugt302C1 and UGT2A2

DIOPT Version :9

• Sequence 1: NP_652626.1
• Gene: Ugt302C1 / 53510
• FlyBaseID: FBgn0040259
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: NP_001099147.2
• Gene: UGT2A2 / 574537
• HGNCID: 28183
• Length: 536
• Species: Homo sapiens
• Alignment Length: 572
• Identity: 170/572 - (29%)
• Similarity: 273/572 - (47%)
• Gaps: 103/572 - (18%)

  Fly    10 FLALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIIS-------------- 60
            |:.:|:|.|.......:..|::.....||:.....:.:.|....|.||:::
Human    13 FVQMLVFNLTLTEVVLSGNVLIWPTDGSHWLNIKIILEELIQRNHNVTVLASSATLFINSNPDSP 77

  Fly    61 ------PFELKKPIKNIKDVPAKSILTSMQGRIANL-LQSSKEPIIKQIINFHEMGIEITELLLK 118
                  |...||  .||..:....|:..:..|...| :.:..:.:.|.:..|.::.|::.:.:||
Human    78 VNFEVIPVSYKK--SNIDSLIEHMIMLWIDHRPTPLTIWAFYKELGKLLDTFFQINIQLCDGVLK 140

  Fly   119 EPSVI-ELMKSNQTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGS-------- 174
            .|.:: .|.|..  ||.::::                |:...|...|:......:.:
Human   141 NPKLMARLQKGG--FDVLVAD----------------PVTICGDLVALKLGIPFMYTLRFSPAST 187

  Fly   175 --------PSPPSYVPSALLKFSDRMSLVERVGNQ-AFLTYEYIFLNY------FYLPRQEVLYR 224
                    |:|.||||:||.:.:|:|:..||:.|. ::...:|||.:|      :|   .::|.|
Human   188 VERHCGKIPAPVSYVPAALSELTDQMTFGERIKNTISYSLQDYIFQSYWGEWNSYY---SKILGR 249

  Fly   225 KYFPNNKQDFYDMRKNTALVLLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGA- 288
               |..   ..:......:.|:..:....|||||.||...|||:|. :..:||||::.|||:.:
Human   250 ---PTT---LCETMGKAEIWLIRTYWDFEFPRPYLPNFEFVGGLHC-KPAKPLPKEMEEFIQSSG 307

  Fly   289 EHGVIYFSMGSNLKSKTLPLEKRQALIDTFAQLKQRVLWKFEDTDLPGKPA----NVFISDWFPQ 349
            ::||:.||:||.:|:  |..||...:....||:.|:|||:::..    |||    |..:.||.||
Human   308 KNGVVVFSLGSMVKN--LTEEKANLIASALAQIPQKVLWRYKGK----KPATLGNNTQLFDWIPQ 366

  Fly   350 DDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAK 414
            :|:|.|....|||||||.....|:|||..|.||:|:|.||..|:|..:..|..|.|:...::|..
Human   367 NDLLGHPKTKAFITHGGTNGIYEAIYHGVPMVGVPMFADQPDNIAHMKAKGAAVEVNLNTMTSVD 431

  Fly   415 LLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYH 479
            ||:|::.:||.|...:....:|..:.||...||:|||:|:|.|.||||||:||.|:.||.:.|||
Human   432 LLSALRTVINEPSYKENAMRLSRIHHDQPVKPLDRAVFWIEFVMRHKGAKHLRVAAHDLTWFQYH 496

  Fly   480 NLDAMLILYGGIIFVLYC----IFLLIRLVWRLLQELFIKKDTSKPKQKAKR 527
            :||.       |.|:|.|    |||:|:..      ||..:...|..:|.||
Human   497 SLDV-------IGFLLVCVTTAIFLVIQCC------LFSCQKFGKIGKKKKR 535

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	124/377 (33%)
UGT2A2	NP_001099147.2	UDPGT	30..524	CDD:278624	162/542 (30%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150182
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm8543
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	9	8.690