DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302C1 and ugt5g2

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_001186305.1	Gene:	ugt5g2 / 556049	ZFINID:	ZDB-GENE-081028-66	Length:	534	Species:	Danio rerio

Alignment Length:	521	Identity:	148/521 - (28%)
Similarity:	251/521 - (48%)	Gaps:	73/521 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 LLSCVSAYNY-LVVLHTAARSHYHVGSALAKGLAAAGHQVTII-----------SPF------EL 64
            |||..|.||. .:::.....||:.....|.|.|.:.||::::|           ||:      .|
Zfish    15 LLSLPSGYNADKILVFPIDGSHWVNMEVLVKKLQSRGHELSVIRLEDSWFIKGNSPYYSSITVTL 79

  Fly    65 KKPIKNIK--DVPAKSILTSMQ-GRIANLLQSSKEPIIKQIINFHEMG-----IEITELLLKEPS 121
            ||...::.  :...|.||.:.: |.|..:|....|     .|...::|     ..:|.:|..:..
Zfish    80 KKKFIDLDLFETAVKKILDARRDGPIMGVLAQMSE-----FIGILKVGHGANIAMLTSMLENKVL 139

  Fly   122 VIELMKSNQTFDAVISE-------VFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGSPSPPS 179
            :.::..:|  :|.::::       :..:..|.....:.:....|.|.|..         :|||.|
Zfish   140 MSQIKMAN--YDLMLTDPAMPGGVILAHYLHLPMVYNVRWMSFGEGHFSI---------APSPIS 193

  Fly   180 YVPSALLKFSDRMSLVERVGNQAFLTY--EYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTA 242
            :||......:|||.|:||..|  ||.|  ..|...:..:|....|...:||.. .|...|:::..
Zfish   194 FVPVPGSGLTDRMGLLERSRN--FLHYGLNLIQERWMVIPMYTSLLLNHFPPG-TDLLTMQRSAE 255

  Fly   243 LVLLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGA-EHGVIYFSMGSNLKSKTL 306
            |.|:.......||||..||::.:||... |..:|||.|:.||::.: :|||:..|:|:.:..  |
Zfish   256 LWLVRADFVFEFPRPSMPNLVYIGGFQC-RPAKPLPADLEEFMQSSGDHGVVVMSLGTLIAG--L 317

  Fly   307 PLEKRQALIDTFAQLKQRVLWKFEDTDLPGKPA----NVFISDWFPQDDILAHDNVLAFITHGGL 367
            |.|..:|:...|||:.|:|:|:|    :..:|:    |..:..|.||:|:|.|....||:.|||.
Zfish   318 PKEVMEAIASAFAQIPQKVIWRF----IGQRPSTLGNNTLLIQWLPQNDLLGHPKTRAFVAHGGT 378

  Fly   368 LSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRV 432
            ....|:|||..|.:|:|:..||..|:.|.:..|....:.....|:.:.|.|:..|:.||...|.:
Zfish   379 NGLYEAIYHGVPVLGLPLLFDQLDNIVRLQARGGARMLDAATCSTKEFLVALTDILENPTYRQNM 443

  Fly   433 RDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAM-LILY------GG 490
            :.:|:.:||:...||::||||:|.|.|:|||.:||:.:.:::...|:.||.: |:|:      ||
Zfish   444 QKLSNLHRDRPLHPLDKAVYWIEFVLRNKGAPHLRAEAYNVSEFSYYCLDVVALVLFMLLGTLGG 508

  Fly   491 I 491
            :
Zfish   509 V 509

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	109/362 (30%)
ugt5g2	NP_001186305.1	egt	3..507	CDD:223071	146/517 (28%)
ugt5g2	NP_001186305.1	UDPGT	25..513	CDD:278624	142/511 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170584640
Domainoid	1	1.000	252	1.000	Domainoid score	I2043
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	252	1.000	Inparanoid score	I3189
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	10	9.690