Protein Alignment Ugt302C1 and UGT2B28

DIOPT Version :9

• Sequence 1: NP_652626.1
• Gene: Ugt302C1 / 53510
• FlyBaseID: FBgn0040259
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: NP_444267.1
• Gene: UGT2B28 / 54490
• HGNCID: 13479
• Length: 529
• Species: Homo sapiens
• Alignment Length: 564
• Identity: 170/564 - (30%)
• Similarity: 274/564 - (48%)
• Gaps: 83/564 - (14%)

  Fly     8 TGFLALL-LFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIIS----------- 60
            |..|.|: |.|..|..|....||  .|...||:.....:.|.|...||:||:::
Human     6 TSVLLLIHLGCYFSSGSCGKVLV--WTGEYSHWMNMKTILKELVQRGHEVTVLASSASILFDPND 68

  Fly    61 PFELKKPI--KNIKDVPAKSILTSMQGRIANL------LQSSKEPIIKQIINFHEMGIEITELLL 117
            .|.||..:  .::.....::|:.....|.:::      |..|:|..|  :..||::.....:.::
Human    69 AFTLKLEVYPTSLTKTEFENIIMQQVKRWSDIQKDSFWLYFSQEQEI--LWEFHDIFRNFCKDVV 131

  Fly   118 KEPSVIELMKSNQTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDLV------GSPS 176
            ....|::.::.:: ||.:.::.|     |...| ..|.|:.:....::.:.....      |...
Human   132 SNKKVMKKLQESR-FDIIFADAF-----FPCGE-LLAALLNIPFVYSLCFTPGYTIERHSGGLIF 189

  Fly   177 PPSYVPSALLKFSDRMSLVERVGNQAFLTY-EYIF-------LNYFYLPRQEVLYRK---YFPNN 230
            ||||:|..:.|.||:|:.:|||.|..::.| ::.|       .:.||   .|||.|.   :....
Human   190 PPSYIPVVMSKLSDQMTFMERVKNMIYVLYFDFWFQMCDMKKWDQFY---SEVLGRPTTLFETMG 251

  Fly   231 KQDFYDMRKNTALVLLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGA-EHGVIY 294
            |.|.:.||.:.         |..||.|:.||:..|||:|. :..:||||::.||::.: |:||:.
Human   252 KADIWLMRNSW---------SFQFPHPFLPNIDFVGGLHC-KPAKPLPKEMEEFVQSSGENGVVV 306

  Fly   295 FSMGSNLKSKTLPLEKRQALIDTFAQLKQRVLWKFEDTDLPGKPANVFISDWFPQDDILAHDNVL 359
            ||:||.:.:.|  .|:...:....|::.|:|||:|:.........|..:..|.||:|:|......
Human   307 FSLGSVISNMT--AERANVIATALAKIPQKVLWRFDGNKPDALGLNTRLYKWIPQNDLLGLPKTR 369

  Fly   360 AFITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIIN 424
            |||||||.....|:|||..|.||||:|.||..|:|..:..|..|.:.:..:||..||.|::.:||
Human   370 AFITHGGANGIYEAIYHGIPMVGIPLFWDQPDNIAHMKAKGAAVRLDFHTMSSTDLLNALKTVIN 434

  Fly   425 NPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDA---MLI 486
            :|...:.|..:|....||...||.|||:|:|.|..|||||:||.|::||.:.|||:||.   :|.
Human   435 DPSYKENVMKLSIIQHDQPVKPLHRAVFWIEFVMCHKGAKHLRVAARDLTWFQYHSLDVIGFLLA 499

  Fly   487 LYGGIIFVL--YCIFLLIRLVWRLLQELFIKKDTSKPKQKAKRN 528
            ....:|||:  :|:|..    |:     |.:|.     :|.||:
Human   500 CVATVIFVVTKFCLFCF----WK-----FARKG-----KKGKRD 529

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	119/366 (33%)
UGT2B28	NP_444267.1	UDPGT	24..525	CDD:278624	160/540 (30%)
		egt	<269..506	CDD:223071	93/239 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165150507
Domainoid	1	1.000	260	1.000	Domainoid score	I1978
eggNOG	1	0.900	-	-		E33208_3BDT1
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	267	1.000	Inparanoid score	I3041
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm8543
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	10	9.690