DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302C1 and Ugt37C1

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_525007.1	Gene:	Ugt37C1 / 53583	FlyBaseID:	FBgn0026754	Length:	485	Species:	Drosophila melanogaster

Alignment Length:	500	Identity:	169/500 - (33%)
Similarity:	259/500 - (51%)	Gaps:	36/500 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    46 AKGLAAAGHQVTIISPFELKKPIKNIK--DVP-AKSILTSMQGRIANLLQSSKEPIIKQIINFHE 107
            ||.||.|||.||::|..:.|...|:|.  .|| .|....:::.::|::..|....|....:..:.
  Fly     4 AKALAEAGHNVTVVSMMQPKVMHKDIHLIVVPVTKEQERTLENQMASMAGSKNNIITTMYLLLNG 68

  Fly   108 MGIEITEL--LLKEPSVIELMKSNQTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISW--- 167
            :.:.:|..  |||:|....:.::.  ||.:|...|.|:...|.|...|.|:|       :.|
  Fly    69 LDVMVTSQADLLKDPRFQRVFETK--FDLMILGSFFNDFQLGVAGKLKVPVI-------VDWMIP 124

  Fly   168 -NT---DLVGSPSPPSYVPSALLKFSDRMSLVERVGN---QAFLTYEYIFLNYFYLPRQEVLYRK 225
             ||   :.|.:||..||||:.....:..||..:|..|   ...|.|..|..||.:    ..:|.:
  Fly   125 SNTMIDEFVANPSEVSYVPNESTFATTPMSFFKRAENLVKHVILKYLTIRFNYKF----NRIYNE 185

  Fly   226 YFPN-NKQDFYDMRKNTALVLLNQHVSLSFP-RPYSPNMIEVGGMHINRKRQPLPKDILEFIEGA 288
            .|.: :.....:|:||.::|.:..|:....| ||..|.:|||||:.:..:..|||:||.:|:|.:
  Fly   186 IFTDKDMPTLSEMKKNISMVFVGSHLISDGPIRPLVPAIIEVGGIQVKEQPDPLPQDIEQFMENS 250

  Fly   289 EHGVIYFSMGSNLKSKTLPLEKRQALIDTFAQLKQRVLWKFEDTD-LPGKPANVFISDWFPQDDI 352
            ..|.|:.|.|||:||..:..|....:....:.|||.|:||:||.: .||..:|:|..||.|||||
  Fly   251 SQGAIFLSFGSNIKSYMVKPEIVGIMFKVLSGLKQNVIWKWEDLENTPGNASNIFYKDWLPQDDI 315

  Fly   353 LAHDNVLAFITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLA 417
            |||.|...|:||.|..|.|||.||..|.|.:|||||..||.|....:||||::..:.::......
  Fly   316 LAHPNTKLFVTHAGKGSITESQYHGVPMVALPIFGDHPLNAALMVNSGYGVSLDLQTITEDTFRE 380

  Fly   418 AIQKIINNPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLD 482
            ||.:::.|.:.||.||..|..|||:..||.:..::||::|.||.||..|:|.:..:.|::.||||
  Fly   381 AINEVLENDKYTQAVRKFSALYRDRPLTPRQSVLFWVDYVLRHHGAPNLQSPAVHMGFVELHNLD 445

  Fly   483 AMLILYGGIIFVLYCIFLLIRLVWRLLQELFIKKDTSKPKQKAKR 527
                :|..::.:|..:..|.||..:.|....:.| ...|.:|.|:
  Fly   446 ----IYALVLAILIFLVFLTRLTVKFLFSKLLGK-AKVPARKKKQ 485

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	131/361 (36%)
Ugt37C1	NP_525007.1	UDPGT	1..477	CDD:278624	166/490 (34%)
Ugt37C1	NP_525007.1	egt	6..433	CDD:223071	152/439 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445745
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D53444at6656
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.850