DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302C1 and Ugt35E2

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_652623.2	Gene:	Ugt35E2 / 53506	FlyBaseID:	FBgn0040255	Length:	527	Species:	Drosophila melanogaster

Alignment Length:	536	Identity:	204/536 - (38%)
Similarity:	319/536 - (59%)	Gaps:	35/536 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LALLLFCLLSCVSAYNYLVVLHTAAR----------SHYHVGSALAKGLAAAGHQVTIISPFELK 65
            :::|:..|:..|.|  .|.||...||          |||:......|.||:.||::|.:|||.||
  Fly     3 MSMLVLRLIVLVVA--LLPVLLEGARILGVFPIPSHSHYYHALPYLKKLASLGHEITSVSPFPLK 65

  Fly    66 KPIKNIKDVPAKSILTSMQGRIANLLQSSKEPIIKQIINFHEMGIEITELLLKEPSVIE--LMKS 128
            :|:.||.|:|...:..:::..:.||..........:.||.:.:|  :.|.:|:...|..  |...
  Fly    66 EPVANIHDIPVPELFDNIEEIVGNLTNRKGTWNEFEYINQYTLG--LVEKVLENDGVRREILQPE 128

  Fly   129 NQTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTD-LVGSPSPPSYVPSALLKFSDRM 192
            :..||.:|.:::..:|.:|.|.:|.||:||:.::|. .|..| |||:.||.:|:.|....:.|..
  Fly   129 SLQFDLIIVDLWRLDALYGLAAYFDAPIIGIASYGT-DWKIDELVGNVSPLAYLQSPSFNWFDLD 192

  Fly   193 SLVERVGNQAFLTYEYIFLNYFYL--PRQEVLYRKYFPN--NKQDFYDMRKNTALVLLNQHVSLS 253
            :...|:|:  |:.....::|:.:.  .|.|.:||||||.  :|:...::.:|.||:|:|||.:::
  Fly   193 TYGGRLGH--FVDQSMAWINWHWRHEERHEAVYRKYFPKIADKRSLSEITRNFALILVNQHFTMA 255

  Fly   254 FPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGA-EHGVIYFSMGSNLKSKTLPLEKRQALIDT 317
            .||||.||:|||||||::::.:.||:|:.:||:|| ||||||||:|:|::|:.|..::|:.||||
  Fly   256 PPRPYVPNIIEVGGMHVDQQPKALPQDLEDFIQGAGEHGVIYFSLGTNVRSRNLSKDRRKILIDT 320

  Fly   318 FAQLKQRVLWKFEDTDLPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPFVG 382
            ||.|.||:||||:..:|...|:||.||.||||.|||||.||..|||||||.||.|.|:...|.:|
  Fly   321 FASLPQRILWKFDADELSDVPSNVLISPWFPQQDILAHPNVKLFITHGGLQSTVECIHRGVPMLG 385

  Fly   383 IPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPL 447
            :|.|.|||.||...:..|.|:.::|.:::|.:....|.:::.......:.:..:||||||...||
  Fly   386 LPFFYDQFRNMEHIKAQGIGLVLNYRDMTSDEFKDTIHQLLTEKSFGVKAKRTADRYRDQPMNPL 450

  Fly   448 ERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDA----MLILYGGIIFVLYCIFLLIRLVWRL 508
            :.|::|..:|.|||||.::|.|.::|:||.||:||.    :|.::..:..|:.|...|:|.:
  Fly   451 DTAIWWTHYVLRHKGAPHMRVAGRNLDFITYHSLDVLGTFLLAVWAILSIVVLCAIKLLRAI--- 512

  Fly   509 LQELFIKKDTSKPKQK 524
               |..||....||||
  Fly   513 ---LKSKKGNISPKQK 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	149/356 (42%)
Ugt35E2	NP_652623.2	egt	23..481	CDD:223071	181/462 (39%)
Ugt35E2	NP_652623.2	YjiC	26..440	CDD:224732	159/418 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445628
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D45181at50557
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	11	10.800