DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302C1 and Ugt303A1

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_001262470.1	Gene:	Ugt303A1 / 53503	FlyBaseID:	FBgn0040252	Length:	526	Species:	Drosophila melanogaster

Alignment Length:	524	Identity:	180/524 - (34%)
Similarity:	299/524 - (57%)	Gaps:	42/524 - (8%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LALLLFCLL--SCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPIKNIKD 73
            |.:|||.||  ...:|.|.|.|......|.|.:.:...:.|...|||:|:||...:...|:.:..
  Fly    12 LTVLLFGLLCPKLTNAENILAVFSYTFGSSYLLITPFLRNLVQRGHQLTLISAVTIMPHIEGVHH 76

  Fly    74 VPAKSILTSMQGRIANLLQSSKEPIIKQIINFHEMGIEIT----------------ELLLKEPSV 122
            :           |:..|     :.::|.:::| |...::|                :.:|::|.|
  Fly    77 I-----------RVPKL-----DMLMKILLDF-EYDTDLTKWTEAQFLSEYFYNCSKFVLEDPGV 124

  Fly   123 IELMK-SNQTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTD-LVGSPSPPSYVPSAL 185
            .||:: ::..:..:|.|...|:|.:||::||.|||:|:..:|: |||.| |||:.:|..|.|.:.
  Fly   125 QELLRNASAKYSLIILEASHNDALYGFSQHFNAPLLGVAAYGS-SWNIDFLVGNSAPSVYEPMSA 188

  Fly   186 LKFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTALVLLNQHV 250
            |.::..::|:|:..|..::|.|.:...:.|||||..||:::||......:|:|:..:|||:|||.
  Fly   189 LGYTSGLNLIEKWHNLIYITEERLVERFIYLPRQIDLYKQHFPGATTSIHDLRRRFSLVLINQHF 253

  Fly   251 SLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGAEHGVIYFSMGSNLKSKTLPLEKRQALI 315
            ::...|...||::||.|||::.|..||..::.:.::.|||||||||||..|....||...|.::.
  Fly   254 TMGRVRSNVPNIVEVAGMHLDEKPYPLDAELKKILDEAEHGVIYFSMGLQLLDHWLPPGMRASMS 318

  Fly   316 DTFAQLKQRVLWKFEDTDLPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPF 380
            |.||||||:|:||.:..::..:..|||...||||..||.|.||..||||.||||..||:::..|.
  Fly   319 DAFAQLKQQVIWKTDYPEMVNQSRNVFARTWFPQRAILNHPNVKLFITHAGLLSLIESVHYAVPL 383

  Fly   381 VGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQT 445
            :.||:|.|||.|..|.|:.|....:.::.|...:::.||:.::.|....:..||:|.|:.||..:
  Fly   384 LCIPLFYDQFQNTKRMEKLGVARKLDFKNLFRDEIVLAIEDLVYNASYKRNARDLSQRFHDQPMS 448

  Fly   446 PLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGI----IFVLYCIFLLIRLVW 506
            .::.|::|.|::.|||||.::|.|.|:::.:||:|:|.:.:|:|.|    |.|::..:.|:.|..
  Fly   449 AMDTAIWWTEYILRHKGADHMRIAEQEMSLMQYYNVDVVSVLFGRIGLSAIIVIFLGWKLVSLAT 513

  Fly   507 RLLQ 510
            |.|:
  Fly   514 RHLE 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	138/350 (39%)
Ugt303A1	NP_001262470.1	egt	26..465	CDD:223071	155/456 (34%)
Ugt303A1	NP_001262470.1	UDPGT	39..507	CDD:278624	166/485 (34%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445616
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D45181at50557
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	11	10.800