DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and Ugt8

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_062149.1	Gene:	Ugt8 / 50555	RGDID:	3938	Length:	541	Species:	Rattus norvegicus

Alignment Length:	519	Identity:	150/519 - (28%)
Similarity:	260/519 - (50%)	Gaps:	40/519 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPIKNIKDV-PA 76
            :||:..:....|...::|......||.::...||..|...||....:        :...:|: |:
  Rat     9 MLLWSAVGIARAAKIIIVPPIMFESHLYIFKTLASALHERGHHTVFL--------LSEGRDIDPS 65

  Fly    77 KSILTSMQGRIAN------LLQSSKEPIIKQIINFHEMGIEITELLLKEPSVIELMKSNQT---- 131
            ..........|.|      .|||.    ::.|.:.....:|:.::|.......::|..||.
  Rat    66 NHYSLQRYPGIFNSTTSDAFLQSK----MRNIFSGRLTAVELVDILDHYTKNCDMMVGNQALIQG 126

  Fly   132 -----FDAVISEVFLNEAHFGFAEHFKAPLIGL--GTFGAISWNTDLVGSPSPPSYVPSALLKFS 189
                 ||.::  |..|:. .||.   .|.|:|:  ..|....|....||:|:|.:|||......:
  Rat   127 LKKEKFDLLL--VDPNDM-CGFV---IAHLLGVKYAVFSTGLWYPAEVGAPAPLAYVPEFNSLLT 185

  Fly   190 DRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTALVLLNQHVSLSF 254
            |||:.:||:.|........:.:::..||:.|.:.:||.....:..||:...::|.:|...|:|.|
  Rat   186 DRMNFLERMKNTGVYLISRMGVSFLVLPKYERIMQKYNLLPAKSMYDLVHGSSLWMLCTDVALEF 250

  Fly   255 PRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGA-EHGVIYFSMGSNLKSKTLPLEKRQALIDTF 318
            |||..||::.|||: :.:...|||:|:..:::|| |||.:..|.|:.:|..:..:..:  |....
  Rat   251 PRPTLPNVVYVGGI-LTKPASPLPEDLQRWVDGAQEHGFVLVSFGAGVKYLSEDIANK--LAGAL 312

  Fly   319 AQLKQRVLWKFEDTDLPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGI 383
            .:|.|:|:|:|..|.......|..:.:|.||:|:|.|.|:.||::||||.|..|::||..|.|||
  Rat   313 GRLPQKVIWRFSGTKPKNLGNNTKLIEWLPQNDLLGHSNIRAFLSHGGLNSIFETMYHGVPVVGI 377

  Fly   384 PIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLE 448
            |:|||.:..|.|.:..|.|:.:.:..::..:|..|:.|:||||...||.:.:|:.::||...|:.
  Rat   378 PLFGDHYDTMTRVQAKGMGILLEWNTVTEGELYDALVKVINNPSYRQRAQKLSEIHKDQPGHPVN 442

  Fly   449 RAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCIFLLIRLVWRLLQEL 512
            |..||::::.||.||.:||||...::|.||..||...:|..|.:.:.:.:..:.:.::|.::.|
  Rat   443 RTTYWIDYILRHDGAHHLRSAVHQISFCQYFLLDIAFVLLLGAVALYFIVSYVTKFIYRKVKSL 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	116/360 (32%)
Ugt8	NP_062149.1	egt	8..490	CDD:223071	148/501 (30%)
Ugt8	NP_062149.1	UDPGT	21..502	CDD:278624	145/501 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166344191
Domainoid	1	1.000	256	1.000	Domainoid score	I1959
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm9018
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.740