DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302C1 and Ugt316A1

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_001287111.1	Gene:	Ugt316A1 / 40079	FlyBaseID:	FBgn0036842	Length:	636	Species:	Drosophila melanogaster

Alignment Length:	514	Identity:	165/514 - (32%)
Similarity:	275/514 - (53%)	Gaps:	19/514 - (3%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FLALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGL--AAAGHQVTIISPFELKK----PI 68
            ||..|| |  ..|...|.|.|..:..:|||..|..|.:.|  ::..|.||:|||...::    .|
  Fly     7 FLGTLL-C--GIVLGANVLTVFPSVWKSHYLFGRRLLQELVESSGNHSVTLISPHAAQEGVDAEI 68

  Fly    69 KNIKDVPAKSILTSM--QGRIANLLQSSKEPIIKQIINFHEMGIEITELLLKEPSVIELMKSNQT 131
            ..|:::..:.:..:.  .|......:...:.::::.......|....::||.:|.|.:|:.|.:.
  Fly    69 PKIRELRIEGLRENWLDMGMSFEAEEMRAQSVMERFTRLIYAGTTNVDILLSDPQVRKLLTSGEK 133

  Fly   132 FDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGSPSPPSYVPSALLKFSDRMSLVE 196
            ||.:|.::||::|..|.|.::..|.:.:...||.||..::.|:|...|..||..|.|::||:..:
  Fly   134 FDLLIVDLFLSDALLGLAFYYGIPTVAVSPTGANSWLNNMFGNPQSSSLDPSNFLPFTERMNTRQ 198

  Fly   197 RVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQD---FYDMRKNTALVLLNQHVSLSFPRPY 258
            |:.|....|:|.:..|:|:|..|:.:|..:|....::   :.|:.||.:|.|:|.|..|.:||.|
  Fly   199 RILNSLMSTFERLTYNFFHLISQQSVYTNHFELLVKELPLYRDLTKNLSLALINSHPGLHYPRAY 263

  Fly   259 SPNMIEVGGMHINRKRQP-LPKDILEFIEGAEHGVIYFSMGSNLKSKTLPLEKRQALIDTFAQLK 322
            .|||:||||:|::..... |||.:|.|:|.|..||||||:|:::::..||.||...::|.|..||
  Fly   264 LPNMVEVGGLHLSHLNDDNLPKHLLSFMESAPSGVIYFSLGADVETAQLPQEKLAIILDVFGHLK 328

  Fly   323 Q-RVLWKFEDTDLPGK---PANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGI 383
            : ..|.|:|..:...:   |.||.|:||:||..||.|..|..||:..|.||..|||..:||.:.|
  Fly   329 EFHFLLKWEKEEFTAEQVLPENVMIADWWPQQAILHHPQVKMFISSCGQLSVWESISGQKPVLAI 393

  Fly   384 PIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLE 448
            ||..:|.:...|.:::|..|||.|:.|:...||..|:::..|....:::..:.:|...:..||:.
  Fly   394 PILAEQEVMAKRLQRHGVSVTVGYDSLAYDSLLHGIRQLTLNTSYVEKLGQLKERLISRDSTPVG 458

  Fly   449 RAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCIFLLIRLVWR 507
            :||..::.:....||.:|:|.:..|||.:...:|.:||:..|...:|...||.|..:.|
  Fly   459 KAVRKIQLILESGGADFLKSHANTLNFWRAEGVDVLLIIAVGFFGILTIPFLAICFILR 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	125/356 (35%)
Ugt316A1	NP_001287111.1	egt	1..480	CDD:223071	153/475 (32%)
Ugt316A1	NP_001287111.1	MGT	39..448	CDD:273616	131/408 (32%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45445640
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	189	1.000	Inparanoid score	I2570
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D45181at50557
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.900