DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302C1 and Ugt49C1

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_001036565.1	Gene:	Ugt49C1 / 37421	FlyBaseID:	FBgn0034605	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	550	Identity:	187/550 - (34%)
Similarity:	297/550 - (54%)	Gaps:	59/550 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLFCLLSCVSAYN---------YLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKP-- 67
            |||.||...:.|:         .|.|.....:||:.:.:||.:.|..:|||||:::.|.|:|.
  Fly     5 LLFGLLLTGTLYSQLELAEGSKILAVYAFPGKSHFMMHTALIRELVESGHQVTMVTAFSLEKEQL 69

  Fly    68 --------IKNIKDVPAKSILTSMQGRIANLLQSSKEPIIKQIINFHEMGIEITELLLKEPSVIE 124
                    |:.:.|......|......:..|.:.:....:|.:   ..:|::.||..|::|.|..
  Fly    70 GSNYTEILIEPVYDFWHDVKLNFGAQHLFELTRMTNYDFLKML---EIIGLKTTEHALRQPKVRS 131

  Fly   125 LMKSNQ---TFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGSPSPPSYVPSALL 186
            |:.:.|   .||.:::|.|..||....|..:|.|::...|.|..:..:.::|..:|.|:||...:
  Fly   132 LIHAEQKEGVFDLLLAEQFYQEAFLALAHLYKIPVVTTSTLGYENHMSQMMGLITPWSFVPHGFM 196

  Fly   187 KFSDRMSLVERVGNQAFLTYEYI--FLNYFYLPRQEVLYRKYF-------PNNKQDFYDMRKNTA 242
            .|:||||.:|||.|.....||.:  .||||  |:.:.:.|::|       |..|.    |.:..:
  Fly   197 PFTDRMSFLERVKNSYASFYEDMDRLLNYF--PKMDAVAREFFGPVLTEVPKVKH----MERQIS 255

  Fly   243 LVLLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGAEHGVIYFSMGSNLKSKTLP 307
            ::|||.|..|:..||....|:.||||||...: |||.|:...::||..|.|:||:|||::||.:|
  Fly   256 VMLLNSHAPLTTARPTVDAMVPVGGMHIYPPK-PLPADMQALLDGATEGAIFFSLGSNVQSKDMP 319

  Fly   308 LEKRQALIDTFAQLKQRVLWKFEDTDLPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLSTTE 372
            :|..:..:..|..|||||||||||..:...|.||.:..|.||.|||||.:|..|||||||..|.|
  Fly   320 VEMLRLFLQVFGSLKQRVLWKFEDESISQLPDNVMVRKWLPQADILAHRHVKVFITHGGLFGTQE 384

  Fly   373 SIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSD 437
            .:::..|.:|||.:.||.|||.:|...||.:::|::.::...|..::.::|:|....:.|:.:||
  Fly   385 GVHYAVPMLGIPFYCDQHLNMNKAVLGGYAISLHFQSITEEILRHSLDQLIHNVTYKENVQRVSD 449

  Fly   438 RYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAM----LILYGGIIFVLYCI 498
            .:||:...|.:.||||:|:|.||:||.::|||..|||:.|::.||.:    :|...|::    .:
  Fly   450 IFRDRPLEPRKSAVYWIEYVIRHRGASHMRSAGLDLNWFQFYLLDVIAFVAIIALAGVM----AL 510

  Fly   499 FLLIRLVWRLLQELFIKKDTSKPKQKAKRN 528
            .|.|||:          ..::|..:|||:|
  Fly   511 SLAIRLL----------MGSNKKHRKAKQN 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	138/360 (38%)
Ugt49C1	NP_001036565.1	egt	22..504	CDD:223071	171/491 (35%)
Ugt49C1	NP_001036565.1	UDPGT	37..498	CDD:278624	168/470 (36%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454729
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D58919at33392
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	11	10.800