DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt-35

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_001023694.1	Gene:	ugt-35 / 3565443	WormBaseID:	WBGene00044286	Length:	536	Species:	Caenorhabditis elegans

Alignment Length:	550	Identity:	139/550 - (25%)
Similarity:	247/550 - (44%)	Gaps:	59/550 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLFCLLSCV----SAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISP-----FELKKPIK 69
            :||.|:|.:    .:.|:||.....|.||:...:.:|..|:..||.||.::|     :|..|.:|
Worm     7 ILFFLISILFQNSKSVNFLVYCPLFAHSHHTFLAKIADTLSEEGHNVTFLAPIIVQKYENFKYLK 71

  Fly    70 NIKDV----PAKSI--LTSMQGRIANLLQSSKEP----IIKQIINFHEMGIEITELLLKEPSVIE 124
            :..|:    |.:.:  |..:.|........::||    :|..|..|.:|..:|.|.|..:.|:::
Worm    72 HTTDIIYIQPDEELKKLGEIMGSAGFSKYWTEEPSVFSMIPSIKLFQKMFHKIYENLRADLSILD 136

  Fly   125 LMKSNQTFDAVISEVFLNEA-----HFGFAEHFKAPLIGLGTFGAISWNTDLVGSPSPPSYVPSA 184
            .:| ::.|||:|.||....|     :.|....:  |...: |.|.:.  :..:|.|:.|:.:.||
Worm   137 SLK-DRKFDAMIYEVLAFNAIAIQQYLGIKTLY--PTFSV-THGMVL--SKSIGEPASPATLSSA 195

  Fly   185 LLKFSDRMSLVERVGNQ--AFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTALVLLN 247
            |..:.::|:..||:.|.  ||: |:     .|..|.:.:.|.  .|..:.|..:.....:.|.||
Worm   196 LSPYGEKMNFQERLMNTVCAFI-YQ-----VFMKPPKMISYS--HPYYEIDLKEAESKASFVFLN 252

  Fly   248 QHVSLSFPRPYSPNMIEVGGMHINRK--RQPLPKDILEFIEGAEHGVIYFSMGSNLKSKTLPLEK 310
            .:..|.||||.....:.:||:.:|..  |:....|....|.......:..|.||.:.|..:|...
Worm   253 SNPYLDFPRPMLTKTVLIGGISVNTSQIREERLSDEYHNILNIRVKTVLISFGSIMLSTDMPDRY 317

  Fly   311 RQALIDTFAQLKQ-RVLWKFE--DTDLPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLSTTE 372
            :..::....:... ..:||:|  :.|......|:....|.||..:||...:.|||||.||.|..|
Worm   318 KSIIVKVIEEFPNVTFIWKYESDELDFANNLKNLHFFKWIPQTALLADSRLSAFITHAGLGSINE 382

  Fly   373 SIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSS-AKLLAAIQKIINNPEATQRVRDMS 436
            ..|..||.:.:|||.||..|.....::...:::..::|.: .||..::.||:.:....:....::
Worm   383 LSYMGKPAILVPIFADQLRNAKMLVRHNGSISLEKQDLGNFEKLRVSLAKILKDNSFQENAEILA 447

  Fly   437 DRYRDQQQTPLERAVYWVEHVSRHKGAKY-----LRSASQDLNFIQYHNLDAMLILYGGIIFVLY 496
            .:..:|..:|.|   ..::|.:  .||::     |...|:.::|...:.:|..|.|...:..::|
Worm   448 RQLNNQPISPRE---LLIKHAT--FGAEFGELPSLDPYSRQMSFFSLNMIDIFLFLGVFLAILVY 507

  Fly   497 CIFLLIRLVWRLLQELFIKKDTSKPKQKAK 526
            .:|..:||   ||..|..||...|.::..|
Worm   508 FLFTFLRL---LLNLLLKKKAVEKSQENRK 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	89/366 (24%)
ugt-35	NP_001023694.1	Glycosyltransferase_GTB_type	2..464	CDD:299143	119/473 (25%)
ugt-35	NP_001023694.1	UDPGT	34..506	CDD:278624	120/490 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810