DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302C1 and Ugt36D1

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_001246082.2	Gene:	Ugt36D1 / 35138	FlyBaseID:	FBgn0032713	Length:	519	Species:	Drosophila melanogaster

Alignment Length:	515	Identity:	169/515 - (32%)
Similarity:	276/515 - (53%)	Gaps:	36/515 - (6%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FLALLLFCLLSCVSAYNYLVVL----HTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPIKN 70
            ||||.|......|.|...|.||    |... ||:|....:.||||.|||.|:::|.|..|.|:.:
  Fly    10 FLALALSQPDELVEAAGPLKVLGLFPHPGV-SHFHFFHPIMKGLAEAGHDVSVVSHFPDKHPVAH 73

  Fly    71 IKDVPAKSILTSMQGRIAN---LLQSSKEPIIKQIINF---HEMGIEITELLLKEPSVIELMKSN 129
            .||.|    ||.|. ::.|   |....|.........|   ::.|.:...|.|:..::.::::..
  Fly    74 YKDFP----LTGMD-KLTNSVDLKFFEKRTFYSHFQEFFLLYDWGKQTCNLTLRSEALQQILRRP 133

  Fly   130 QTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGSPSPPSYVPSALLKFSDRMSL 194
            ..||.:|.|.|..:...|.|...:||:|.|.:...:.|:.:.:|:|..||::|:..:..|..|:.
  Fly   134 GRFDVIIMEQFNTDCMMGVAHQLQAPVIALSSCVMMPWHYERMGAPLIPSHIPALFMAQSQHMNF 198

  Fly   195 VERVGNQAFLTYEYIFLNYFY----LPRQEVLYRKYFPNNKQDFYDMRKNTALVLLNQHVSLSFP 255
            ..|:.|. |.|:.   ||:.|    :|..:.:.:..|.::.....::.|||::..:|||.|||.|
  Fly   199 GGRLANW-FSTHA---LNWMYKLLSVPAADAMVQYKFGHDVPSVGELVKNTSMFFVNQHYSLSGP 259

  Fly   256 RPYSPNMIEVGGMHINRKRQPLPKDILEFIEGAEHGVIYFSMGSNLKSKTLPLEKRQALIDTFAQ 320
            :...||:||:||:|| :|.:|||.|:...::.||.|||..|.||.:::.:|...||..:|...|:
  Fly   260 KVTPPNVIELGGIHI-QKSKPLPADLQRILDNAEEGVILISWGSMIRANSLSAAKRDGIIRAVAR 323

  Fly   321 LKQRVLWKFEDTDLPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPI 385
            |||:|:||:|:..||.:|.|:.|..|.||.|||.|.||..|::||||:.|:|:.|...|.|..|:
  Fly   324 LKQKVIWKWENETLPNQPPNMHIMKWLPQRDILCHPNVKVFMSHGGLMGTSEAAYCGVPVVATPM 388

  Fly   386 FGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLERA 450
            :||||:|.|...:.|.|..:::|::....::.|::|.::. :.....:.:|..:..:.|..|..|
  Fly   389 YGDQFVNTAALVERGMGTILNFEDIGENTVMRALKKALDK-KFHDAAKVVSHSFHHRPQQALHTA 452

  Fly   451 VYWVEHVSRHKGAKYLRSASQDLNFIQYHNLD--AMLILYGGIIFVLYCIFLLIRLVWRL 508
            ::|||||:...||..|:.::.:::...|::||  |:|.|..|.|...:        ||.|
  Fly   453 IWWVEHVAHTGGAPLLKPSAVEMSRFVYYSLDVYAVLALVLGSIIASW--------VWLL 504

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	119/352 (34%)
Ugt36D1	NP_001246082.2	egt	21..482	CDD:223071	154/472 (33%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45454600
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.890