DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302C1 and Ugt301D1

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_001246079.1	Gene:	Ugt301D1 / 35105	FlyBaseID:	FBgn0032684	Length:	530	Species:	Drosophila melanogaster

Alignment Length:	544	Identity:	180/544 - (33%)
Similarity:	286/544 - (52%)	Gaps:	51/544 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FLALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPIKNIK-- 72
            ::.:.|..||...:....|.:....|.||:.........|...||.||.::....|.|.:|:.
  Fly    10 WMLIFLIGLLEFGAGSRILFMGPFPAPSHWLWLEHFQNDLLRQGHHVTSVNNHPTKHPHENLTEI 74

  Fly    73 ------DVP---AKSILTSMQGRIANLLQSSKEPIIKQIINFH---EMGIEITELLLKEPSVIEL 125
                  |:|   .|..:.|||             .:....|..   .:|:..||...|:|.|.:|
  Fly    75 IISPSFDIPKHFPKENIFSMQ-------------FVSDFNNLELWWTIGLMTTEHAFKDPKVKKL 126

  Fly   126 MKS-NQTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGSPSPPSYVPSALLKFS 189
            ::| :..:|.||.|.|.:||...|.:.|..|::.:||.|........:|..:|.|.:|..||..:
  Fly   127 IESKDDHYDLVIIEQFFHEAFLMFGKRFNCPVVTIGTMGYADNIDHAMGILTPWSLIPHLLLSHT 191

  Fly   190 DRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQ----DFYDMRKNTALVLLNQHV 250
            |||:..:|..|.....|:.:...:.|||:.:.|..|||..:.:    :..|:.:|.:|||:|.|.
  Fly   192 DRMTFGQRAYNAYLSLYDAVMRRWVYLPKMQKLAEKYFQGSIEGPLPNVLDLERNISLVLINAHR 256

  Fly   251 SLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGAEHGVIYFSMGSNLKSKTLPLEKRQALI 315
            |:..|||..|.:|:|||.||.:.:| ||.|:..|::.|.:|||||||||.:||..||.||...::
  Fly   257 SIDLPRPSMPGLIDVGGAHIQKPKQ-LPTDLQNFLDNATYGVIYFSMGSYVKSTDLPQEKTALIL 320

  Fly   316 DTFAQLKQRVLWKFEDTDLPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPF 380
            ..|.||||:|:||||:..:...|:||.|..|.||:|||||.||..||||||:..|.|.||...|.
  Fly   321 KAFGQLKQQVIWKFENDSIGDLPSNVMIKKWMPQNDILAHPNVKLFITHGGIFGTQEGIYWGVPM 385

  Fly   381 VGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQT 445
            :.:|::|||..|..::.:.||..::.:.:|::..|:..|:.:||:|:..:...::|.|:||....
  Fly   386 LCVPLYGDQHRNTIKSVREGYARSLVFSKLTTDDLVRNIETLINDPQYKRSALEVSQRFRDNPIH 450

  Fly   446 PLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCI----FLLIRLVW 506
            ||:.|.:|:|::.||:||::|:|....:...||..||           ||.|:    ||.|.|.|
  Fly   451 PLDEATFWIEYIIRHRGARHLKSHGAFIPLHQYLLLD-----------VLGCLLLGAFLAIWLPW 504

  Fly   507 RLLQEL---FIKKDTSKPKQKAKR 527
            |:::.:   ::|.::|....:.|:
  Fly   505 RMIRRVHKWWLKGESSNKLNEGKK 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	137/353 (39%)
Ugt301D1	NP_001246079.1	egt	12..483	CDD:223071	164/484 (34%)
Ugt301D1	NP_001246079.1	UDPGT	37..483	CDD:278624	159/459 (35%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	76	1.000	Domainoid score	I3136
eggNOG	1	0.900	-	-		E33208_3BDT1
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	89	1.000	Inparanoid score	I2281
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		mtm6444
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	P	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
	9	8.860