Protein Alignment Ugt302C1 and Ugt1a1

DIOPT Version :10

• Sequence 1: NP_652626.1
• Gene: Ugt302C1 / 53510
• FlyBaseID: FBgn0040259
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: NP_036815.1
• Gene: Ugt1a1 / 24861
• RGDID: 3935
• Length: 535
• Species: Rattus norvegicus
• Alignment Length: 546
• Identity: 156/546 - (28%)
• Similarity: 264/546 - (48%)
• Gaps: 56/546 - (10%)

  Fly    13 LLLFCLLSCV-----SAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISP----------- 61
            |||.|||.||     |....|:|:.... ||:.....:.:.|...||:|.:|:|
  Rat    12 LLLPCLLLCVLGPSASHAGKLLVIPIDG-SHWLSMLGVIQQLQQKGHEVVVIAPEASIHIKEGSF 75

  Fly    62 FELKK---PIKNIKDVPAKSILTSMQGRIANLLQSSKEPIIKQIINFHEMGIEITELLLKEPSVI 123
            :.::|   |.:| ::|.|..:   ..||..    ..::|.:.:::..:......:.:||...|.:
  Rat    76 YTMRKYPVPFQN-ENVTAAFV---ELGRSV----FDQDPFLLRVVKTYNKVKRDSSMLLSGCSHL 132

  Fly   124 ----ELMKS--NQTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGS--PSPPSY 180
                |.|.|  ...|||::::.||..... .|::...|.:..  ..|:..:.||..:  |:|.||
  Rat   133 LHNAEFMASLEQSHFDALLTDPFLPCGSI-VAQYLSLPAVYF--LNALPCSLDLEATQCPAPLSY 194

  Fly   181 VPSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLP----RQEVLYRKYFPNNKQDFYDMRKNT 241
            ||.:|...:|||:.::||.|......|.......|.|    ..|:|.::.      ...|:....
  Rat   195 VPKSLSSNTDRMNFLQRVKNMIIALTENFLCRVVYSPYGSLATEILQKEV------TVKDLLSPA 253

  Fly   242 ALVLLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGA-EHGVIYFSMGSNLKSKT 305
            ::.|:.......:|||..|||:.:||::..:|: .|.::...::..: |||::.||:||.:..
  Rat   254 SIWLMRNDFVKDYPRPIMPNMVFIGGINCLQKK-ALSQEFEAYVNASGEHGIVVFSLGSMVSE-- 315

  Fly   306 LPLEKRQALIDTFAQLKQRVLWKFEDTDLPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLST 370
            :|.:|...:.:...::.|.|||::..|.......|..:..|.||:|:|.|....|||||.|....
  Rat   316 IPEKKAMEIAEALGRIPQTVLWRYTGTRPSNLAKNTILVKWLPQNDLLGHPKARAFITHSGSHGI 380

  Fly   371 TESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDM 435
            .|.|.:..|.|.:|:||||..|..|.|..|.|||::..|:::..|..|::.:|||....:.:..:
  Rat   381 YEGICNGVPMVMMPLFGDQMDNAKRMETRGAGVTLNVLEMTADDLENALKTVINNKSYKENIMRL 445

  Fly   436 SDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCIFL 500
            |..::|:...||:.||:|||:|.|||||.:||.|:.||.:.|||:||.:..|   :..||..:|:
  Rat   446 SSLHKDRPIEPLDLAVFWVEYVMRHKGAPHLRPAAHDLTWYQYHSLDVIGFL---LAIVLTVVFI 507

  Fly   501 LIRLVWRLLQELFIKKDTSKPKQKAK 526
            :.:......::.|..|...|...|:|
  Rat   508 VYKSCAYGCRKCFGGKGRVKKSHKSK 533

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	Glycosyltransferase_GTB-type	<185..507	CDD:471961	102/326 (31%)
Ugt1a1	NP_036815.1	UDPGT	30..526	CDD:278624	144/519 (28%)