DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302C1 and ugt-3

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_506203.2	Gene:	ugt-3 / 191174	WormBaseID:	WBGene00013903	Length:	529	Species:	Caenorhabditis elegans

Alignment Length:	540	Identity:	137/540 - (25%)
Similarity:	242/540 - (44%)	Gaps:	49/540 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISP-----FELKKPIKNIK 72
            |||.........:|||::......||......:|..||.|||.||:..|     :..||.:||..
Worm     4 LLLLAFFPVAFGFNYLIISPVFGYSHMKFMGRIADILADAGHNVTLFQPIIYDYYAHKKIVKNPN 68

  Fly    73 ------DVPAKSILTSMQGRIANLL---QSSKEPIIKQIINFHEMGIEITELLLKEPSVIELMK- 127
                  :|..:....:.:..:....   :.||.||....|...::..|...:..|.....||.:
Worm    69 IEVINYEVDEEEKAAASEASVFKFFWKAKGSKNPISSAKITSEKLYKEFEHICRKMLLDKELHRW 133

  Fly   128 -SNQTFDAVISEVF-LNEAHFGFAEHFKAPL---IGLGTFGAISWNTDLVGSPSPPSYVPSALLK 187
             .::.||:.|||.| ....:.|.....|:|:   .|: ..||.|:   .||.|.|.:|:|:....
Worm   134 ILSKNFDSHISEAFDFCGLYLGDFLKLKSPIPLYSGV-RCGAASY---AVGEPIPLNYLPTEGSN 194

  Fly   188 FSDRMSLVERVGNQAFLT-YEYIFLNYFYLPRQEVLYRKYFP-------NNKQDFYDMRKNTALV 244
            :..:.|.::|:.:...|| |.:.|         .:|:.|.:.       .|.:.:.::.:::...
Worm   195 YGKKSSAIDRLSDMLGLTGYHFQF---------GILFDKQYDQAYRLTGGNVRTWQEILQSSTFF 250

  Fly   245 LLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGAEHGVIYFSMGSNLKSKTLPLE 309
            |.|.:..|||..|....:|::||..|...:.....:....|....:..|..|.|:.::|..:|.:
Worm   251 LTNSNPYLSFSTPTISKVIQIGGFTIESFKTTTLDEEFNKILSLRNNTILVSFGTVIQSSDMPDD 315

  Fly   310 KRQALIDTFAQLKQRV-LWKFEDTD--LPGK-PANVFISDWFPQDDILAHDNVLAFITHGGLLST 370
            .:..||:.|.::.... :||:|:.|  |..| ..||.:|.|.||..:||...:..|:|||||.||
Worm   316 FKTGLIEAFRRMPDATFIWKYEEDDKTLKNKLSENVVLSKWIPQPALLADSRLDLFVTHGGLGST 380

  Fly   371 TESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVH--YEELSSAKLLAAIQKIINNPEATQRVR 433
            .|..|.....:.:|:|.||.:|.....::| |..|:  ::.:.|.||:..||.|:||.:..:..:
Worm   381 MEVGYAGVSSIMVPVFSDQGVNAEMLARHG-GAIVYDKFDLVDSKKLMETIQMILNNSDYRKNSK 444

  Fly   434 DMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCI 498
            .:||...:|...|.:..:...|..:|......|...:...|||:::.||::.::...|..|...:
Worm   445 RLSDILHNQPMDPKQVLLNHCEFAARFAQVDNLEPYANKYNFIEFYCLDSLALVVCTISVVALVM 509

  Fly   499 FLLIRLVWR-LLQELFIKKD 517
            |.::..|.. ::::|.:||:
Worm   510 FKILSFVVNSVIEKLKLKKE 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	96/368 (26%)
ugt-3	NP_506203.2	egt	1..457	CDD:223071	121/466 (26%)
ugt-3	NP_506203.2	UDPGT	27..525	CDD:278624	128/511 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810