DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt-56

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_506074.2	Gene:	ugt-56 / 188073	WormBaseID:	WBGene00011453	Length:	524	Species:	Caenorhabditis elegans

Alignment Length:	534	Identity:	116/534 - (21%)
Similarity:	216/534 - (40%)	Gaps:	95/534 - (17%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 CV--SAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPF-------ELKKPIKNIKDVPA 76
            |:  ||::.|:......:||.:..:.:|..|||.||:||:|...       ||...|..|..|..
Worm    13 CIYGSAFDILIYAPRMMQSHVYFTARIANVLAARGHKVTVIDNVFRYDVDNELSSDIHEIISVEP 77

  Fly    77 KSILTSM--QGRIANLLQSSK------EPIIKQIINFHEMGIEITELLLKEPSVIELMKSNQTFD 133
            ...:|.:  .|.:..:|.:||      ..|::.:.:.|.  ::.|.|:.....:.:|.:..  ||
Worm    78 SPEVTKLLNTGSLPTILWNSKASPEEQRTIMEGLGHVHR--LQCTHLIENSTLIPKLQEIK--FD 138

  Fly   134 AVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGSPSPPSYV------------PSALL 186
            ..|.||| :....|..|     :||:       ..|.:|.|..|...|            ||.|.
Worm   139 FAIHEVF-DSCGVGILE-----VIGV-------QKTVIVSSTGPMDVVPITLGISDTLNTPSLLS 190

  Fly   187 KFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEV--LYRKYFPNNKQDFYDMRKNTALVLLNQH 249
            .:...:|..|:..|..||:.   .||:..:....:  |::||: ..|:...::.:...|:..|.|
Worm   191 DYGSYLSFFEKRRNLKFLSG---MLNFHEMQDSMISPLFKKYY-GLKKPTGEIMRQANLLFYNIH 251

  Fly   250 VSLSFPRPYSPNMIEVGGMHINRKR-----------QPLPKDILEFIEGAEHGVIYFSMGSNLKS 303
            ......|.......::||:....::           .|.||.::.|             |:...|
Worm   252 EGSDGMRMRGRRSFDIGGIAFKDQKNLTMEYQTLLSDPRPKVLVSF-------------GTAATS 303

  Fly   304 KTLPLEKRQALIDTFAQLKQRV-LWKFEDTDLPGK----PANVFISDWFPQDDILAHDNVLAFIT 363
            ..:|...:.:|:....|:...: :||:|..|...|    ..|:....:.||.|:||...:..|:|
Worm   304 SHMPQNLKNSLMTAMKQMNNVLFIWKYEMEDNFTKQEELTTNIIFKKFLPQTDLLASSKIDLFVT 368

  Fly   364 HGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSS-AKLLAAIQKIIN-NP 426
            |.|..|..|:.......:.:|:||||..|...|.:||....:...::.: ||::.|::..:. |.
Worm   369 HCGQNSLLEAFNSGVRVLAVPLFGDQHRNAKLAFENGLIEILPKSDIETPAKIVKAVKTGLEPNA 433

  Fly   427 EATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQY---HNLDAMLILY 488
            :..|.:..:|...|:.::......:..:|       |.|  |.....||.::   ::.:.::.|.
Worm   434 KLDQNIVLISSLLRNSKENAENLLISTIE-------ATY--STEFPPNFSKFPKNYHPNTLVRLI 489

  Fly   489 GGIIFVLYCIFLLI 502
            ...|.:::.:|:.:
Worm   490 DSSIALVFMLFIFV 503

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	80/380 (21%)
ugt-56	NP_506074.2	Glycosyltransferase_GTB_type	<216..>399	CDD:299143	42/196 (21%)
ugt-56	NP_506074.2	Glycosyltransferase_GTB_type	<353..453	CDD:299143	27/99 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.810