DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt-59

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_501911.1	Gene:	ugt-59 / 187799	WormBaseID:	WBGene00011238	Length:	506	Species:	Caenorhabditis elegans

Alignment Length:	523	Identity:	135/523 - (25%)
Similarity:	219/523 - (41%)	Gaps:	69/523 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TGFL-ALLLFC-LLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTI-ISPFELKKPIK 69
            |.|| .:||.| :::.....|.|..:.|.:.||....:.||:.||.:|||||: ::..:....|:
Worm     2 TQFLFKILLVCTIINEFYTLNILFYVPTLSHSHISFNTKLAQLLATSGHQVTVLLAQVDDALLIE 66

  Fly    70 NIKD---------VPAKSILTSMQGRIANLLQSSKEPIIKQIINFHE----MGIEITELLLKEPS 121
            |..|         ||        :|.:..:|.|:..|        :|    :...|...|||...
Worm    67 NATDFAVLRKKVGVP--------RGHLRQVLWSNPGP--------YEDSSPLNPRIFYKLLKVSG 115

  Fly   122 VIELMKSNQTFDAV-ISEVFLNEAHFGFAEHFKAPLIGLGTFGAIS-----W---------NTDL 171
            .......|..||.: :|.:...:...|..|.:.:  .|.|.|.:|.     |         ..:.
Worm   116 TFVTACQNMAFDHLFLSSLQQQKFDVGLVEQYDS--CGFGIFKSIGIENTVWLSATAIYRPQAEA 178

  Fly   172 VGSPSPPSYVPSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYD 236
            :|...|.||||.....|||:||..::|.|..........|:.|....|..::     ..:|....
Worm   179 LGVHLPYSYVPELFAHFSDKMSFFQKVINILIGQATSFVLDVFVQGFQSRIF-----GFEQGLGA 238

  Fly   237 MRKNTALVLLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGAEHGVIYFSMGSNL 301
            :.:.|:.||:|......:..|.|.....:||:.::::.:.|........:.||:|.:..|.|...
Worm   239 ISQETSSVLINSVPFFDYSMPVSHQFSNIGGITVDKRDKKLDPYWQSIADSAENGFVLVSFGGIA 303

  Fly   302 KSKTLPLEKRQALIDTFAQLKQ-RVLWKFE--DTDLPGKPANVFISDWFPQDDILAHDNVLAFIT 363
            ::..:....::...|:||:... ..:.|:|  .......|.||.::.|.||..::||.|....||
Worm   304 RTVDMTESMQRIFYDSFARFSHITFIVKYETSSNSTISVPDNVILTPWIPQLPLMAHKNYKTIIT 368

  Fly   364 HGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEA 428
            |||..|..|:..|.||.:.:|:|.|...|...||..|..|.:....||..:::.||..|:.||:.
Worm   369 HGGWSSILETTMHSKPMILMPLFADHAKNSKVAESKGVAVLLDKMRLSRRRVVHAIYTILTNPKY 433

  Fly   429 TQRVRDMSDRYRDQQQTPL--ERAVYW----VEHVSRHKGAKYLRSASQDLNFIQ--YHNLDAML 485
            ||.....|..:.|   ||:  |..:.|    ....||...||:||....|.::::  :..:.||
Worm   434 TQNCEKFSRMFSD---TPIPHEELIEWRIRQAAKPSRKAFAKHLRPKEPDFSYLKLGFLIIPAM- 494

  Fly   486 ILY 488
            |||
Worm   495 ILY 497

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	95/372 (26%)
ugt-59	NP_501911.1	UDPGT	33..490	CDD:278624	121/482 (25%)
ugt-59	NP_501911.1	Glycosyltransferase_GTB_type	<247..492	CDD:299143	66/247 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	1	1.100	-	-	O	PTHR48043
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.910