DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt-47

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_505595.2	Gene:	ugt-47 / 187570	WormBaseID:	WBGene00011006	Length:	536	Species:	Caenorhabditis elegans

Alignment Length:	531	Identity:	140/531 - (26%)
Similarity:	238/531 - (44%)	Gaps:	65/531 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTII---------SPFELKK 66
            ||:|.|  .....||..||.....::||......:|..||.|||.||::         |....|.
Worm    10 LAILYF--FEYGLAYKILVFSPATSKSHLISNGRIADELAKAGHNVTLLEIDFLGIVDSTKSAKL 72

  Fly    67 PIKNIKDVPAKSILTSMQGRIANLLQSSKE---------PIIKQIINFHEMGIEITELLLKEPSV 122
            ..|.|..||.|     ||| ..|::||..|         .::|..|.:..:..::.|..|:...:
Worm    73 VKKTIVRVPKK-----MQG-FKNVIQSFSEGVMEDEGLFELLKGNIAYQTVYNDLCEEFLENEVM 131

  Fly   123 IELMKSNQTFDAVISEVFLNEAHFGFAEHF---KAPLIGLGTFGAISWNTDLVGSPSPPSYVPSA 184
            ...:| ::.|||..:|. ||...||:|:..   :..||....|  .|...|....|:|.:.|| .
Worm   132 FNKLK-DENFDAFFAEQ-LNICGFGYAKALGIQRKFLISSCPF--FSHVYDYTSHPAPYASVP-F 191

  Fly   185 LLKFSDRMSLVERVGN-QAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTALVLLNQ 248
            :...|...:.:||..| ...:|....|  ||...|...::||.|.::.....::.:|..::.|..
Worm   192 ISDMSPEPTYLERTNNLLRGITINTFF--YFSHNRLTSIFRKKFGDDFPAITEIVRNVDIIFLAT 254

  Fly   249 HVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGAEHGVIYFSMGSNLKSKTLPLEKRQA 313
            ...:.|..|..||::.|||:.::.....:.......::..:.||||||:|:...:.|  ::|:
Worm   255 DEIIDFSSPTLPNLVHVGGLGVDDDTTEMGPVFEAEMKKGDKGVIYFSLGTIANTST--IDKK-- 315

  Fly   314 LIDTFAQLKQRVLWKFED--------------TDLPGKPANVFISDWFPQDDILAHDNVLAFITH 364
            ::::|.:    ::.||.|              .|...:.:|||:|||.||..||.|..:..||||
Worm   316 VMESFLE----IVKKFPDYHFLIRADKNDKNTKDKATEISNVFVSDWLPQPAILHHPRLRTFITH 376

  Fly   365 GGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSA--KLLAAIQKIINNPE 427
            .|.....|:.....|.:.||...||.||....|:.|:|:....::..:.  .:..||::::.||.
Worm   377 AGYNGLMEAALAGVPLITIPFMFDQNLNSRAIEKKGWGIRRDKKQFLTEPNAIEEAIREMLTNPS 441

  Fly   428 ATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAML----ILY 488
            .|::...:.|..|::.....:|.:...|.|.::.|...|.:..:||:.|:|:|||.::    :.:
Worm   442 YTKQAHRVRDLMRNKPMGARDRFIKTTEWVIQNGGVHELLTEGRDLSIIKYYNLDIIVPCFFVAF 506

  Fly   489 GGIIFVLYCIF 499
            ..|||..:.:|
Worm   507 YFIIFPFFKLF 517

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	93/368 (25%)
ugt-47	NP_505595.2	UDPGT	23..527	CDD:278624	134/516 (26%)
ugt-47	NP_505595.2	egt	<230..509	CDD:223071	72/286 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14096
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810