DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt-34

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_505728.2	Gene:	ugt-34 / 185120	WormBaseID:	WBGene00009255	Length:	526	Species:	Caenorhabditis elegans

Alignment Length:	550	Identity:	150/550 - (27%)
Similarity:	249/550 - (45%)	Gaps:	76/550 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FLALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISP-----FELKKPIK 69
            |...||..|.....:|||||.....|.||:...:.:|..|..|||.||.:.|     :|..|.::
Worm     8 FSLFLLHLLPQLTLSYNYLVFCPLFAHSHHKFLAKIADTLTEAGHNVTFLMPIIHREYENVKYLE 72

  Fly    70 NIKDV----PAKSILTSMQGRIANLLQSSKEPI---IKQIINFHEMGIEITELLLKEPSVIELMK 127
            :..|:    |.|.:....|....:....:...|   |..|..|..|..::.::|.|:.||::.:|
Worm    73 HTTDIVYIQPDKELEEIAQNADYSTFWKNDFGILTFIPAIERFFRMFTKVHDILKKDLSVLDNLK 137

  Fly   128 SNQTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWN----TDL---VGSPSPPSYVPSAL 185
             |:.|||:|.|.....|| ...|:.:...|      ..||:    |:|   :|.||.|:::|..:
Worm   138 -NRKFDAMIFESLAFCAH-PIREYLEIKTI------FPSWSMTHMTELSQAIGEPSSPTFLPITI 194

  Fly   186 LKFSDRMSLVERVGNQ-AFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTALVLLNQH 249
            ..|.|:|:..||:.|. |..|:.:||       :...|....:|:...||.::......:..|.:
Worm   195 SPFGDKMTFKERLLNTLADFTFTHIF-------QPPTLTSFKYPHQTFDFKEILSQAPFIFFNSN 252

  Fly   250 VSLSFPRPYSPNMIEVGGMHIN---RKRQPLPKDILEFIEGAEHGVIYFSMGSNLKSKTLPLEKR 311
            ..|.||||.....||:||:.:|   .:.:.||::....:...:..|: .|.||.|:|..:|:|.:
Worm   253 PFLDFPRPTLTKTIEIGGISVNATLMRLEKLPEEYNTILNLKQQNVL-ISFGSMLRSSEMPVEYK 316

  Fly   312 QALIDTFAQLKQ-----RVLWKFEDT------DLPGKPANVFISDWFPQDDILAHDNVLAFITHG 365
                ||.||:.:     ..:||:|:.      :||    |.....|.||..:||...:.|||||.
Worm   317 ----DTIAQVVRSFPSVTFIWKYENNNVEFAENLP----NFHFFKWVPQTALLADSRLSAFITHA 373

  Fly   366 GLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLA-AIQKIINNPEAT 429
            ||.|..|..|..||.:.:|||.||..|.....::...:.:..::|....:|. |:..|:|:...|
Worm   374 GLGSINELSYIGKPAILVPIFADQLRNAKMLVRHNGSIELDKKDLGKFDVLRDAVDAILNDKSYT 438

  Fly   430 QRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQD-----LNFIQYHNLDAMLILYG 489
            .....:|.:...|..:|.:..|.:.|.     |||:....|.|     ::|..:..:|.:|.|
Worm   439 NNAILLSQQLESQPFSPHDLLVKYAEF-----GAKFGELPSLDPHYRKMSFFSFFMIDIILFL-- 496

  Fly   490 GIIFVLYCIFLLIRL-VWRL-LQELFIKKD 517
               ...:.||:.|.| ::|: .:.:|::|:
Worm   497 ---TATFAIFVSISLYLFRVFFKSVFVRKE 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	105/371 (28%)
ugt-34	NP_505728.2	UDPGT	35..518	CDD:278624	138/516 (27%)
ugt-34	NP_505728.2	Glycosyltransferase_GTB_type	<248..500	CDD:299143	74/270 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810