DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302C1 and ugt-40

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_504810.2	Gene:	ugt-40 / 184292	WormBaseID:	WBGene00017331	Length:	526	Species:	Caenorhabditis elegans

Alignment Length:	549	Identity:	140/549 - (25%)
Similarity:	236/549 - (42%)	Gaps:	65/549 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly     9 GF-LALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISP-----FELKKP 67
            || |.|....|:|..::||.||.......||......||..|..|||.||:.||     |.....
Worm     3 GFSLYLYYLLLISSTTSYNILVFCPLFGHSHSTFFGRLADILTEAGHNVTLFSPTIIDEFRNYSY 67

  Fly    68 IKNIKDV----PAKSILTSMQGRIANLLQSSKE---------PIIKQIINFHEMGIEITELLLKE 119
            .|..|||    |:..:..     |.:|:..:|.         .|.:....|..:..|...:|...
Worm    68 TKLTKDVAYLDPSPELKA-----IGDLIAGNKRWWNQEFSVFEIPQTTRFFKSITREQNNVLANN 127

  Fly   120 PSVIELMKSNQTFDAVISE----------VFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGS 174
            .::::.:|..: ||.::.|          .:|....|..|:......|.||..|      |.|.:
Worm   128 LALLDGLKQKK-FDLILFESVFTCALPLMEYLEIKSFAVAQSIAYEPITLGALG------DTVMT 185

  Fly   175 PSPPSYVPSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRK 239
                |::|:.:.:.||:|||.||:.|    |.....||.:.:..:   |.:.:.|.::..|.:.|
Worm   186 ----SHIPNLMAQSSDKMSLCERMLN----TLIQAMLNVYGMTPE---YYQSYTNPEKKIYTLEK 239

  Fly   240 --NTALVLLNQHVSLSFPRPYSPNMIEVGGMHIN----RKRQPLPKDILEFIEGAEHGVIYFSMG 298
              ..:.:.:|.:..|.|||......|::||:.:|    :....|.::..:.:...|. .:..|.|
Worm   240 LSEASFIFMNSNPFLDFPRATITKNIQIGGISVNLDTLKSSGKLTEEWDQILNLREK-TLLVSFG 303

  Fly   299 SNLKSKTLPLEKRQALIDTFAQLKQ-RVLWKFEDTD---LPGKPANVFISDWFPQDDILAHDNVL 359
            |.:.|:.:|...:..|.:...||.. ..:||:|..|   ......|:..|.|.||.::||...:.
Worm   304 SVILSQDMPFAYKVGLTNAMKQLNDVTFIWKYEGDDKKEFANGIKNIHFSKWVPQRELLADPRLS 368

  Fly   360 AFITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLA-AIQKII 423
            ||:|||||.|..|..|..||.:..|:.|||..|....|::...:.....:|.:.|::| |.:||:
Worm   369 AFMTHGGLGSVNEVSYFGKPTIMCPLSGDQMRNAKMLERHNGSIEFSKYDLHNEKVVANAFRKIL 433

  Fly   424 NNPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILY 488
            .:...|...:.:|:..:.|...|.|..:..||..:|......|...|:.:.||||..:|...|:.
Worm   434 YDESYTLSAKRLSEHLQFQPVKPKELFLKHVEFAARFGKLPSLDPYSRQMGFIQYFLIDIAFIVL 498

  Fly   489 GGIIFVLYCIFLLIRLVWRLLQELFIKKD 517
            ..::.::..::.:::.|...|:.. ||.|
Worm   499 TVVLTIVSVLYFVLKFVASCLKAK-IKTD 526

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	92/369 (25%)
ugt-40	NP_504810.2	YjiC	22..447	CDD:224732	112/448 (25%)
ugt-40	NP_504810.2	Glycosyltransferase_GTB_type	<247..503	CDD:299143	70/256 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810