DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt-36

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_504820.2	Gene:	ugt-36 / 184266	WormBaseID:	WBGene00017315	Length:	533	Species:	Caenorhabditis elegans

Alignment Length:	540	Identity:	141/540 - (26%)
Similarity:	228/540 - (42%)	Gaps:	72/540 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLFCLL--SCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPIKNIKDVPA 76
            |||||.  .|..:||:||.......||....:.:|..|..|||.||..:|..::| ...|:.|
Worm    10 LLFCLFFALCSDSYNFLVFCPLFGHSHTTFFAKIADTLTYAGHNVTFFTPTIVRK-FSKIQYV-- 71

  Fly    77 KSILTSMQ----GRIANL--------------LQSSKEPIIKQIINFHEMGIEITELLLKEPSVI 123
            |||...:|    .|:..|              ..||...::..|..|:.|.:|...::.:...|:
Worm    72 KSITHVLQLDPSDRLVKLGSMFEEKDVSKFWYRDSSLSEMLPMIDTFNNMFVEQAAVISRNLHVL 136

  Fly   124 ELMKSNQTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWN-TDLVGSPSPPSYVPSALLK 187
            :.:| ...||.:|.|.|:..|:. ..::.:.......|..|..:| ...:|.|...|.||....:
Worm   137 DDLK-EMNFDVMIFEHFVEPAYL-VLDYLEIQKFIPATSLAFDYNMVKSIGEPLMLSTVPLPTSE 199

  Fly   188 FSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFP-----NNKQDFYDMRKNTALVLLN 247
            :||||||.:|:.|   .....||.|  .:|:.:  ||.|.|     |.|    .:....:.|..|
Worm   200 YSDRMSLPQRLIN---AINPLIFDN--LIPKNK--YRSYRPPYAPINTK----SIEPFCSAVFTN 253

  Fly   248 QHVSLSFPRPYSPNMIEVGGMHIN---RKRQPL-----------PKDILEFIEGAEHGVIYFSMG 298
            .:..:.:||......::|||:.::   .|.|.:           ||.:|            .|.|
Worm   254 SNPYIDYPRATLEKNVQVGGISVDIDKLKSQKVSNEWDAVLNLRPKTVL------------VSFG 306

  Fly   299 SNLKSKTLPLEKRQALIDTFAQLKQ-RVLWKFE--DTDLPGKPANVFISDWFPQDDILAHDNVLA 360
            |.:.||.:|:..:..:.....:... ..:||:|  ||.......|:..|:|.||..:||...:.|
Worm   307 SIMLSKDMPINNKITIATVLGKFPDVTFIWKYETNDTSFANGTENIHFSNWVPQTALLADPRLSA 371

  Fly   361 FITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSA-KLLAAIQKIIN 424
            |.||.||.|..|..|..||.:..|||.||..|.....::...:.:...:||:. |:..|:.||:.
Worm   372 FFTHAGLGSVNEVSYLGKPTIMCPIFADQMRNAKMLARHNGSIEISKYDLSNGDKIEEALSKILF 436

  Fly   425 NPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYG 489
            :.........::.:..:|...|.|..|...|..::......|...|:.::||||..:|...|:..
Worm   437 DESYKTAAEKLAHQLANQPVKPKELLVRHAEFAAQFGHLPSLDPHSRQMSFIQYFLIDLTAIILS 501

  Fly   490 GIIFVLYCIFLLIRLVWRLL 509
            .:|..|:.:|.|.:|::..|
Worm   502 TVILFLFVLFKLGKLMYSKL 521

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	92/372 (25%)
ugt-36	NP_504820.2	Glycosyltransferase_GTB_type	6..507	CDD:299143	136/524 (26%)
ugt-36	NP_504820.2	YjiC	25..455	CDD:224732	114/457 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810