DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt-21

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_001293944.1	Gene:	ugt-21 / 183141	WormBaseID:	WBGene00007885	Length:	534	Species:	Caenorhabditis elegans

Alignment Length:	549	Identity:	144/549 - (26%)
Similarity:	258/549 - (46%)	Gaps:	59/549 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISP-----FELKKPIKNIKD 73
            :|..::||||:|..|:..:....||..|.:|.|..|..||:.||::.|     ...|..:|:.|:
Worm     9 ILTSIISCVSSYKILLYSNLFGHSHVKVLAAAADILTDAGNNVTVLMPVFDNNLRNKTSLKSTKN 73

  Fly    74 V-------PAKSILTSMQGRIANLLQSSKEPIIKQIINFHEMGIEITE---LLLKEPSVIELMKS 128
            .       ..:.:::.|:..:||..:......|..:....:||....|   .::.||.::|.:|:
Worm    74 TIFVEAGPNVEELMSDMRQFLANAWKEDTGNPITMMKAAQDMGTAFAEQCTKVISEPGLLEKLKA 138

  Fly   129 NQTFDAVISEVF------LNEAHFGFAEHFKAPLIGLGTFGAISWNTDLVGSPSPPSYVPSALLK 187
             :.:|..|:|.|      |.|| .....|     :.:.|.......||::|.|...||||....:
Worm   139 -ENYDLAITEPFDTCGYALFEA-INIRAH-----VAILTANRFDHVTDVIGQPIASSYVPGTQSE 196

  Fly   188 FSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNK------QDFYDMRKNTALVLL 246
            ..|||::.||:||.    ::::..:||:    .::..:.|...|      :.:..:....:.:|.
Worm   197 TGDRMTMGERLGNY----FQFLVGSYFF----SLIGDRDFEAAKSVVPITRSWRAILPEASFILT 253

  Fly   247 NQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKD-----ILEFIEGAEHGVIYFSMGSNLKSKTL 306
            ||...|.||.|....::.:||:.:..:::.|..|     ||    |.....::.|.|||.||..:
Worm   254 NQIPLLDFPAPTFDKIVPIGGLSVKTEKKNLKLDEKWSKIL----GIRKNNVFISFGSNAKSVDM 314

  Fly   307 PLEKRQALIDTFAQLKQRV-LWKFEDTDLP--GKPANVFISDWFPQDDILAHDNVLAFITHGGLL 368
            |.|.:.:|.|.|..:.... :||:|:|..|  ....||.:.||.||:::||...:..|:|||||.
Worm   315 PDEFKNSLADVFKSMPDTTFIWKYENTSDPIVNHLDNVHLGDWLPQNELLADPRLSVFVTHGGLG 379

  Fly   369 STTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLL-AAIQKIINNPEATQRV 432
            |.||......|.|.||:|.||..|....:::|..|.:....|:....: ..::|:|.:|:..:..
Worm   380 SVTELAMMGTPAVMIPLFADQGRNAQMLKRHGGAVVIEKNNLADTHFMKETLEKVIKDPKYLENS 444

  Fly   433 RDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYC 497
            :.:::...:|...|.|..:.:||..:|......|.:..:..::|:|..||.:.||....:|.||.
Worm   445 KRLAEMLTNQPTNPKETLIKYVEFAARFGKLPSLDNYGRHQSYIEYFFLDIIAILAVISLFSLYI 509

  Fly   498 IFLLIRLVWRLLQELFIKKDTSKPKQKAK 526
            .::::|.|   ::::|..| .|:.|.|.:
Worm   510 SYIILRAV---IRKIFFSK-CSEVKSKTE 534

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	99/369 (27%)
ugt-21	NP_001293944.1	UDPGT	32..526	CDD:278624	134/516 (26%)
ugt-21	NP_001293944.1	egt	<263..504	CDD:223071	68/244 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810