DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302C1 and ugt-7

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_504343.2	Gene:	ugt-7 / 182577	WormBaseID:	WBGene00015739	Length:	530	Species:	Caenorhabditis elegans

Alignment Length:	541	Identity:	145/541 - (26%)
Similarity:	246/541 - (45%)	Gaps:	81/541 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVT-----IISPFELKKPIKN 70
            |..|.| .|....|:.||::....:.||....|.:|..||..||:|.     |:.....||.|||
Worm     3 LVFLTF-FLQYSYAFKYLIISPIYSYSHVKFMSNIADTLADHGHEVVVFQQQIVEALRDKKVIKN 66

  Fly    71 --IKDV---------------PAKSIL---TSMQGRIANLLQSSKEPIIKQIINFHEMGIEITEL 115
              ||.:               |..|:.   |:.|....:......|.:.|.:   ..|.:::.|
Worm    67 PDIKIINYEANTAGKEFYRNRPKSSVTKYWTTNQAANPSAADQFAEAMSKDL---EHMCLQVFE- 127

  Fly   116 LLKEPSVIELMKSNQTFDAVISEVFLNEAHFGFAEHFKAP--LIGLGT--FGAISWNTDLVGSPS 176
               :.|:..::|| :.||.:::|.| :.......::.|.|  ::.:.:  ...:.|   .:|.||
Worm   128 ---DKSLHTMLKS-EHFDVLLAEPF-DPCGLYLGDYLKIPSTIVAMASSRIDPVQW---ALGQPS 184

  Fly   177 PPSYVPSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPN--NKQDF---YD 236
            ..:::|....|:.:...:.:|:.|        ::: :|...|   ::|..:.|  :|..|   .:
Worm   185 GLNFIPGPDSKYGEESGVWDRINN--------VWM-FFMRTR---MFRAVYWNLLDKLRFKTGLE 237

  Fly   237 MRK------NTALVLLNQHVSLSFPRPYSPNMIEVGGMHINR---KRQPLPKDILEFIEGAEHGV 292
            :|.      .:|.:..|.:..|.||.|.....:.:||..:|.   |.:.||:::...:: .....
Worm   238 IRNIDEIVAESAYLFYNSNPYLDFPFPSLTKCVPIGGFSMNTTNWKSENLPENLKNILQ-KRPNT 301

  Fly   293 IYFSMGSNLKSKTLPLEKRQALIDTFAQLKQRV--LWKFE---DTDLPGK-PANVFISDWFPQDD 351
            ::.|.||.::|..:|.|.:.|:|:. .:|...|  :||:|   |.::.|. |.||.:..|.||..
Worm   302 VFISFGSVIRSADMPQEYKNAIIEV-TKLMSDVTFIWKYEDEKDEEMRGNIPENVHLMKWLPQPA 365

  Fly   352 ILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYE-ELSSA-K 414
            :||...|..|||||||.|..|..|..||.:.||:|.||.:|.....::| |..|:.: |||:| |
Worm   366 LLADSRVSLFITHGGLGSIMEVAYSGKPAIVIPLFFDQPMNGEMLRRHG-GAEVYSKFELSNAKK 429

  Fly   415 LLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYH 479
            |...||.:|.||:.....:.:|:..:.|...|:||.|...|..:..|....|...|:.|||.|:.
Worm   430 LKKVIQNMIQNPKYLANAKKLSNLLQKQPINPIERLVKHAEFAAEFKKLPELDPYSRHLNFFQFF 494

  Fly   480 NLDAMLILYGGIIFVLYCIFL 500
            .||.:..|.  |:|:|..:|:
Worm   495 FLDIVATLL--ILFMLSALFV 513

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	100/374 (27%)
ugt-7	NP_504343.2	egt	1..477	CDD:223071	131/501 (26%)
ugt-7	NP_504343.2	UDPGT	27..521	CDD:278624	138/516 (27%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810