DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302C1 and ugt-27

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_491436.1	Gene:	ugt-27 / 182508	WormBaseID:	WBGene00015694	Length:	526	Species:	Caenorhabditis elegans

Alignment Length:	547	Identity:	149/547 - (27%)
Similarity:	248/547 - (45%)	Gaps:	65/547 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    10 FLALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPIKNIKDV 74
            |...|.|.|:..|::.|.||.....|.||.:..:.||..|..|||.||.:.|         |.||
Worm     4 FFYFLRFLLIFQVNSINVLVYSPAFAASHTNFMARLADTLTEAGHNVTFLVP---------IVDV 59

  Fly    75 PAKSILTSMQGRIANLLQSSKEPIIKQIINFHEM-----------------------GIEI-TEL 115
             |::....:......::....|...::.:.|.:.                       |::: .|.
Worm    60 -ARTKQLGVHVTTDVIIVEKDEHTTQESVPFDDSMEAYWTEETHSSNVGESFQWFFDGMKLGCEN 123

  Fly   116 LLKEPSVIELMKSNQTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDL----VGSPS 176
            ||:...:::.:|| :.||..|.|. |:....|.|:..:   ||.....:.....|.    :|.|.
Worm   124 LLRRHEILDQLKS-RNFDVAIVEP-LSVCGLGLAKKLE---IGKTILASSCAYYDYLFRHIGEPD 183

  Fly   177 PPSYVPSALLKFSDRMSLVERVGN----QAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDM 237
            ..||:||.:....|.|:..||:.|    :|..|..|...:     .::.:|||:|.:...|:.|:
Worm   184 VHSYLPSLMSTTGDVMTTFERLENHRVAEAMATAMYKMFD-----SEKAIYRKHFGDEIPDWRDL 243

  Fly   238 RKNTALVLLNQHVSLSFPRPYSPNMIEVGGMHINRKR---QPLPKDILEFIEGAEHGVIYFSMGS 299
            ....:|...|.:..|.||||.....:.:||:.::.|:   |.|.|:....:......:: .|.||
Worm   244 LPAASLYFTNSNPYLDFPRPILQKTVSIGGISVDTKKIKSQELDKEWNHILNKRNLNML-ISFGS 307

  Fly   300 NLKSKTLPLEKRQALIDTF-AQLKQRVLWKFE--DTDLPGKPANVFISDWFPQDDILAHDNVLAF 361
            .:.|..:..:.::.||... ::.....:||:|  ||.......|::.|.|.||..:|....:.||
Worm   308 MIHSSHMLDDAKKNLIKVIKSEPNVTFIWKYETNDTSFAFGIDNIYFSKWVPQSKLLNDARLTAF 372

  Fly   362 ITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLL-AAIQKIINN 425
            :|||||.||.|..:..||.|.:||||||:.|....:::|..:.|...|||:.|:: :|::.::.:
Worm   373 LTHGGLGSTNELAHFGKPAVMVPIFGDQYRNGHMLQRHGCAIIVQKTELSNWKIVSSAVKSVLYD 437

  Fly   426 PEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLI-LYG 489
            ....:....::|..::|...|.|..|.:||.|:|......:.:..:.|||||.:.||..|| |:|
Worm   438 ENYKKNAAHLADLLQNQPVKPKEIVVKYVEFVARFGPFPEMDAYGRQLNFIQRNLLDVYLIELFG 502

  Fly   490 GIIFVLYCIFLLIRLVWRLLQELFIKK 516
            ..:|.| .||.||.|   .|:...||:
Worm   503 HFLFFL-IIFCLIPL---QLKRWLIKR 525

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	99/363 (27%)
ugt-27	NP_491436.1	UDPGT	21..500	CDD:278624	131/499 (26%)
ugt-27	NP_491436.1	egt	<230..478	CDD:223071	71/248 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810