DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302C1 and ugt-50

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_741913.1	Gene:	ugt-50 / 181413	WormBaseID:	WBGene00011564	Length:	523	Species:	Caenorhabditis elegans

Alignment Length:	539	Identity:	132/539 - (24%)
Similarity:	246/539 - (45%)	Gaps:	57/539 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLFCLLS------CVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPIKNIK 72
            :.|||.:      .|:|...||...:.::||..:.|..|..|..|||...:..| ...|.:.|..
Worm     9 MFFCLTALLHGSFIVNAAKILVYCPSISKSHVLLCSKYADLLHNAGHDTVLFIP-SYSKLLDNYD 72

  Fly    73 DVPAKSI---------LTSMQGRIANLLQSSKEPIIKQIINFHEMGIEI-TELLLKEPSVIELMK 127
            ......:         ..:..|.:||::::|....|.::....:..|:: .:||.|.|.:..::
Worm    73 GAKHAKVWRLHNVTEAYDTKLGTLANVMENSHIGFIDRLTFDADFWIDMCADLLGKLPEMQHII- 136

  Fly   128 SNQTFDAVI-SEVFLNEAHFGFAEHFKAP----LIGLGTFGAISWNTDLVGSPSPPSYVPSALLK 187
             :..||.|| :|:  :.........|..|    |........::||   :|.|:.||||||....
Worm   137 -DYKFDLVIYNEI--DPCTPAIVRLFNIPKTVLLSSEAIMDKVAWN---LGLPTLPSYVPSVEEN 195

  Fly   188 FS-DRMSLVERVGNQAFLTYEYIFLNYFYLPRQEV----LYRKYFPNNKQDFYDMRKNTALVLLN 247
            .: ||||..||:.| .:..::.|.::|.    |::    |:||...::.....::.:|.:|||:|
Worm   196 PNHDRMSFFERMSN-VYKFFQSIVVHYL----QDIHVLNLFRKEVSSDFPSIAEIIRNVSLVLVN 255

  Fly   248 QHVSLSFPRPYSPNMIEVGGMHINR-KRQPLPKDILEFIEGAEHGVIYFSMGSNLKSKTLPLEKR 311
            .......||.||...:.||.:...: :...|||...::.:..:.|.::.|.|:....::||...:
Worm   256 TDEIFDLPRSYSSKFVYVGMLEAGKDENVTLPKKQDDYFKKGKSGSVFVSFGTVTPFRSLPERIQ 320

  Fly   312 QALIDTFAQLKQR--VLWKFEDTDLPGK----PANVFISDWFPQDDILAHDNVLAFITHGGLLST 370
            .::::...:|...  |:....|.:...:    ..||.:.||.||..:|.|.|:..|::|||:.|.
Worm   321 LSILNAIQKLPDYHFVVKTTADDESSAQFFSTVQNVDLVDWVPQKAVLRHANLKLFVSHGGMNSV 385

  Fly   371 TESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDM 435
            .|::|:..|.|.:|:|.|||.|....|:.|.|..|..|.:.......||..::.....:..|:.:
Worm   386 LETMYYGVPMVIMPVFTDQFRNGRNVERRGAGKMVLRETVVKETFFDAIHSVLEEKSYSSSVKRI 450

  Fly   436 SDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCIFL 500
            |...:::..|..||...|::.|.:::.:::....|.:|:.|::::||         :|...||..
Worm   451 SHLMKNKPFTSEERVTKWIDFVLKYETSEHFDLESNNLSIIEHNHLD---------LFFYLCIIS 506

  Fly   501 LIRLVWRLLQELFIKKDTS 519
            |:..|  :.:::|.:|..|
Worm   507 LLNFV--VYRKIFKRKSQS 523

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	93/365 (25%)
ugt-50	NP_741913.1	egt	9..475	CDD:223071	119/478 (25%)
ugt-50	NP_741913.1	UDPGT	26..520	CDD:278624	125/517 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14789
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810