DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt-57

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_509182.1	Gene:	ugt-57 / 180969	WormBaseID:	WBGene00017154	Length:	558	Species:	Caenorhabditis elegans

Alignment Length:	565	Identity:	130/565 - (23%)
Similarity:	222/565 - (39%)	Gaps:	117/565 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPF------ELKKP-- 67
            :.:||..|...|::.|.||.|....:...::...||:.||...|.|..|.|.      .|.||
Worm     3 ILILLLGLTQIVTSLNILVFLLGTNQFERNIFEFLAQQLALRHHNVISIKPVLIPEEPRLVKPKL 67

  Fly    68 ----IKNIKDVPAKSILTSMQGRIANLLQSSK-------EPIIKQIINFHEMGIEITELLLKEPS 121
                .|.||:|..|.:...::..:.|....|.       ||..|                ....|
Worm    68 HLVREKVIKNVLNKDLFKPLEDAVPNAAWRSTYDFDNYLEPYYK----------------AHNAS 116

  Fly   122 VIELMKSN-------QTFDAVISEVFLNEAHFGFAEHFKA-PLIGLGTFGAISWNTDLVGSP--- 175
            ..:|:.||       ::.|..|  |:..........|..| |.|...|.|.........|:|
Worm   117 CYKLLNSNLVDSLKKESLDLAI--VYSGNPCLNALTHLVAVPTIYFDTEGLTDETLIAAGAPIDL 179

  Fly   176 -SPPSY------------------------------VPSALLKFSDRMSLVERVGNQAFLTYEYI 209
             :|||:                              :|:.....|.|..|::......|.| :|.
Worm   180 LTPPSHCFIAESKGYPILNLYKNSVCYFQEMIAQLGLPAVSSLVSSRHRLLDEPITNIFRT-DYT 243

  Fly   210 FLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTALVLLNQHVSLSFPRPYSPNMIEVGGMHINRKR 274
            ....|          |.|||    ...:::.:|...:|....|..||....|:|.|||:||:..:
Worm   244 IKKRF----------KNFPN----VNTLKQQSAAYFVNTDPLLEPPRALPLNVIPVGGLHIDHPK 294

  Fly   275 QPLPKDILEFIEGAEHGVIYFSMGSNLKSKTLPLEKRQALIDTFAQLKQ-RVLWK------FEDT 332
             ||.......|..|:.|:|..|.|:...|..:.....:|::.....|.. |:.|:      .:..
Worm   295 -PLFSPWNTTIASAKEGLIIVSFGTQADSSKMSEYHAKAILKALTNLNDYRIYWRIGPNMHLDGI 358

  Fly   333 DLPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAE 397
            |:...|.::.::.:.||:|:|||.:...|:|:||:.|..|::.|..|.||:|::|....|:.:..
Worm   359 DIEKIPKHINLTTFIPQNDLLAHKSCKLFVTNGGMSSVMEAVAHGVPIVGVPLYGSNRYNLQKVS 423

  Fly   398 QNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKG 462
            ..|.|:.:..::|:...|..|::|::.:.:.....::||..::.:..:|...|::.::|:.||..
Worm   424 NKGLGIVIDKDDLNEISLYGAMKKVLESAKYKNTAKEMSKEFKSRTTSPFAAALHVIDHIGRHHS 488

  Fly   463 AKYLRSASQDLNFIQYHNLDAMLILYGGII---------FVLYCI 498
            ..|::.|.|.:    |..:|..|:|.  ||         |..:||
Worm   489 FAYMQPAFQPI----YTRVDFYLLLL--IILLPVIPLHLFFTFCI 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	89/397 (22%)
ugt-57	NP_509182.1	GT1_Gtf-like	<168..477	CDD:340817	72/324 (22%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	4	3.910