DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Ugt302C1 and ugt-5

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_506200.1	Gene:	ugt-5 / 179753	WormBaseID:	WBGene00013906	Length:	534	Species:	Caenorhabditis elegans

Alignment Length:	558	Identity:	158/558 - (28%)
Similarity:	259/558 - (46%)	Gaps:	83/558 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLFCLL--SCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPF--ELKKP---IKN- 70
            |:|.||  ..|::||:||:......||....:.:|..||.||||||...||  ||.|.   |||
Worm     8 LIFVLLFIKNVASYNFLVISPVYGFSHMKSMAIIANQLADAGHQVTYFQPFVVELFKDHDLIKNP 72

  Fly    71 -------------IKDVPAKSIL----TSMQGRIANLLQSSKEPIIKQIINFHEMGIEITELLLK 118
                         .|::|..|:|    ||.:.: :::.|....|.|     .|:...|:...:.:
Worm    73 NIEIMNYFHDEEGKKNIPGHSVLSDAWTSYKYQ-SDVGQKIFAPRI-----LHQSFQEMCRHMFE 131

  Fly   119 EPSVIELMKSNQTFDAVISEVFLNEAHFGFAEHFKAP-LIGLGTFGAISWNTDLVGSPSPPSYVP 182
            :.::...:| ::.||.|:||.| :......|::.:.| :|.:.|...::..|:.:|.||...|:|
Worm   132 DEALHRQLK-DKKFDVVLSETF-DFCGLYLADYLEMPAIISVFTGNRLNAITNALGEPSFLHYLP 194

  Fly   183 SALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTA---LV 244
            |....|:..|||.:|            |.|:::.......:.:.|.....|.|.:....|   ..
Worm   195 SPSSSFNANMSLYDR------------FNNFWHKILSSSTFGELFDRQYADVYRLTNGKARHWKQ 247

  Fly   245 LLNQ---HVS-----LSFPRPYSPNMIEVGGMHINRKR-QPLPKDILEFIEGAEHGVIYFSMGSN 300
            :||.   |.|     |.|..|....:|.:||..::.|: .|:.|| |:.|.......::.|.|:.
Worm   248 ILNDVTYHFSNSNPYLDFVIPTIAKVIPIGGYTMDYKQVPPVSKD-LDTILNLRSSTVFISYGTM 311

  Fly   301 LKSKTLPLEKRQALIDTFAQLKQ-RVLWKFEDTD----LPGKPANVFISDWFPQDDILAHDNVLA 360
            :.:|.:|.|.:|::||.|...|. ..|||:|:.:    ....|.||.:|.||||..:||...|..
Worm   312 ISAKYMPDEYKQSMIDFFKDNKNVTFLWKYEEPEEKFIKENIPDNVHLSTWFPQQSLLADKRVKL 376

  Fly   361 FITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKII-- 423
            |||||||.||.|..|..||.:..|:|.||..|....|::|....:...::.:.|..:.:.|.:
Worm   377 FITHGGLGSTMELAYSAKPAIVTPLFADQPSNAQMLERHGSVEVLSKHDIPNWKKQSDLLKTMLA 441

  Fly   424 --NNPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLI 486
              ...||..|:.|:   ..:|..:|.|..:...|:.:|......|...::|:.||:::|:|  ||
Worm   442 DKKYQEAATRLADI---LNNQPISPRELMLKHAENAARFGKIPSLTPFAKDMGFIEFYNID--LI 501

  Fly   487 LYGGIIFVLYCIFLLIRLVWRLLQELF-IKKDTSKPKQ 523
            :| .:.|.|:.|::.|        |:| |.|:..|.::
Worm   502 IY-SVSFTLFAIYVTI--------EIFGIVKNCCKTRK 530

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	101/370 (27%)
ugt-5	NP_506200.1	egt	6..509	CDD:223071	150/527 (28%)
ugt-5	NP_506200.1	UDPGT	32..527	CDD:278624	148/529 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810