DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt-33

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_505692.2	Gene:	ugt-33 / 179464	WormBaseID:	WBGene00007946	Length:	522	Species:	Caenorhabditis elegans

Alignment Length:	556	Identity:	164/556 - (29%)
Similarity:	259/556 - (46%)	Gaps:	78/556 - (14%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 TGFLALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELK-----KP 67
            |.||..|.  |:..|..:||||.....|.||:...:.:|..|..|||.||.::|..|:     |.
Worm     4 TLFLCTLF--LVGFVQPFNYLVFCPLYAHSHHKFLAKIADTLTDAGHNVTFLAPIVLRKYENVKY 66

  Fly    68 IKNIKDV----PAKSI----LTSMQGRI----ANLLQSSKEPIIKQIINFHEMGIEITELLLKEP 120
            :::.||:    |:|.:    .||...:.    |..:|     .:..:..|.:|.:::.|.|.|:.
Worm    67 LESTKDIVYIQPSKELEALGFTSNYSKFWTEDATAIQ-----FVPAVRTFVKMFVQLYEDLKKDL 126

  Fly   121 SVIELMKSNQTFDAVISEVFLNEAHFGFAEH--FKAPLIGLGTFGAISWNTDL---VGSPSPPSY 180
            ||::.:| |:.|||::.| ||....|..||:  .||.|..|    :::.:|.:   :|.||.|:.
Worm   127 SVLDELK-NRNFDAIVFE-FLCPTAFPIAEYLGIKALLPSL----SMTHHTQMSRWIGEPSSPTV 185

  Fly   181 VPSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFY-LPRQEVLYRKYFPNNKQDFYDMRKNTALV 244
            :||.:..|.|.|:..||:||    |...:|...|. :||......   |..|.|||:|......:
Worm   186 LPSMISSFGDDMNFWERLGN----TLGDVFFTLFVDMPRMTSFSD---PERKIDFYEMSVRAPFM 243

  Fly   245 LLNQHVSLSFPRPYSPNMIEVGGMHIN---RKRQPLPKDILEFIEGAEHGVIYFSMGSNLKSKTL 306
            .:|.:..|.:.||.....:.:||:.:|   .|::.|.:...:.|...:..:: .|.||.:.||.:
Worm   244 FMNSNPYLDYARPILTKTVLIGGISVNVTQLKQKKLNEKYDKIISERQQNIL-ISFGSMIFSKDM 307

  Fly   307 PLEKRQALIDTFAQLKQ-RVLWKFEDTD------LPGKPANVFISDWFPQDDILAHDNVLAFITH 364
            |...:..|:........ ..:||:|:.|      ||    |:..|.|.||..:||...:.||:||
Worm   308 PDVYKNTLVQVIKSFPNVTFIWKYEEDDVSFAKHLP----NLHFSKWVPQTALLADSRLSAFVTH 368

  Fly   365 GGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSS-AKLLAAIQKIINNPEA 428
            .||.|.||..|..||.|.||:|.||..|.....::...:|:...:||| .||..||..|:|:...
Worm   369 AGLGSVTELSYMGKPAVLIPLFADQLRNSKTLSRHNGSITLSKYDLSSFEKLRFAINTILNDERY 433

  Fly   429 TQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKY-----LRSASQDLNFIQYHNLDAMLILY 488
            ......:|.:.:||..:|....|...|.     ||||     |...|:.::||.::.||  :|::
Worm   434 KINAEILSQQLQDQPVSPHALLVKHAEF-----GAKYGELPNLDPCSRQMSFISFYMLD--IIVF 491

  Fly   489 GGIIFVLYCIFLLIRLVWRLLQELFIKKDTSKPKQK 524
            .|.|.:...|.:::.:.|       |.|...|.|||
Worm   492 VGFILITTTIGIVLTVKW-------ILKFCFKQKQK 520

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	112/370 (30%)
ugt-33	NP_505692.2	Glycosyltransferase_GTB_type	1..498	CDD:299143	156/525 (30%)
ugt-33	NP_505692.2	UDPGT	31..520	CDD:278624	151/525 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14625
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	6	5.810