DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt-51

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_504388.2	Gene:	ugt-51 / 178905	WormBaseID:	WBGene00015369	Length:	524	Species:	Caenorhabditis elegans

Alignment Length:	574	Identity:	134/574 - (23%)
Similarity:	233/574 - (40%)	Gaps:	108/574 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly     7 QTGFLALLLFCLLSC-VSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKPIKN 70
            |..|.||.:..:|.. ::|.|.:..::...:||...|.:|...|...||.|.::        |..
Worm     3 QIHFCALTILAVLPLFLNAANIVFFINAIGKSHLDFGDSLIDSLKEKGHTVDLV--------IAR 59

  Fly    71 IKDVPAKSILTSMQGRI-------------ANLLQSSKEPIIKQIINFHE---MGIEITELLLKE 119
            |.|: ||....|...|.             .|.|.|..|.....|..|.:   :|.::.|:.|.:
Worm    60 INDL-AKGNENSKADRFYTLGFKNGSSWHKLNHLTSPFENNPFPIDGFRQYTLIGNQLCEIALHD 123

  Fly   120 PSVIELMKSNQTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAI---SWNTDLVGSPSPPSYV 181
            ..:.:.: |.:::|..:..||   .:.|.....||.:..:.||.|:   |..|..:|.|:..|.|
Worm   124 EKLHQFL-SEKSYDVGVVSVF---DYCGIGILNKAGVSSITTFNAVPLMSIQTVTIGLPNIASQV 184

  Fly   182 PSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLP----RQEVLYRK-YFPN-------NKQDF 234
            ......| |..:|..::.|  .:|:.:|  |:..:|    .||:|::| |.|:       :|.|.
Worm   185 VPLFYTF-DLATLSGKLWN--LITWAHI--NFHQIPTLRKEQELLFQKVYGPSFSINEVIDKVDL 244

  Fly   235 YDMRKNTAL---VLLNQHVSLSFPRPYSPNMIEVGGMHINRKRQPLPKD--ILEFIEGAEHGVIY 294
            ..:..|..:   :|:|..:..            :||:::   :.|.|.|  :...:..:.:|.|.
Worm   245 SFVNSNEIMETPMLINHRIQY------------IGGINL---KTPKPVDHHLDNLLSKSSNGTII 294

  Fly   295 FSMGSNLKSKTLPLEKRQALIDTFAQLKQ-RVLWK----------FEDTDLPGKPANVFISDWFP 348
            ||.|:.:.....|....:..:..|.:..: ..|||          |||.:      ||.:.||.|
Worm   295 FSFGTQIPGAVYPRYAVRNFVKVFKKYPEYTFLWKYNVQPGEEKLFEDAE------NVILLDWLP 353

  Fly   349 QDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSA 413
            |.|:|....|:.||:|.||.|..|:.|..||.:.||:|.||..|.......|....::..:||..
Worm   354 QTDLLYDPRVIGFISHVGLNSFNEASYAGKPIIAIPLFADQPHNARNGVARGTTYLLNKSKLSEE 418

  Fly   414 KLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGA-KYLRSASQDLNFIQ 477
            .:...::.|:.:...|:..|.:.....::...|.:|.|.|:|:.:.:.|. |........:..|:
Worm   419 SIENGLRAILFDKSYTESARKLQKMLVEKPTKPKDRFVEWMEYAAVNPGLHKIFALPGAKMGNIE 483

  Fly   478 YHNLDAMLILYGGIIFVLYCIFLL-------IRLVWRLLQELFIKKDTSKPKQK 524
            |:.:|.::.:....:...|..|.:       ||||             .|||.:
Worm   484 YYCVDTIVFIAFSCVTFTYIFFKMAKFSLSFIRLV-------------KKPKHE 524

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	92/380 (24%)
ugt-51	NP_504388.2	UDPGT	43..505	CDD:278624	115/500 (23%)
ugt-51	NP_504388.2	egt	<217..496	CDD:223071	70/299 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810