DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt-24

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_500931.3	Gene:	ugt-24 / 177380	WormBaseID:	WBGene00016762	Length:	528	Species:	Caenorhabditis elegans

Alignment Length:	552	Identity:	142/552 - (25%)
Similarity:	244/552 - (44%)	Gaps:	73/552 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPF----ELKKPIKNIKD 73
            :.:|.||:....|..|:..:....||..|.:.:|..|..|||.|||..|.    :|.|.....|:
Worm     8 VFIFKLLNAALPYKILIYSNLYGHSHIKVLNTVADTLTDAGHNVTIFRPIIESSQLDKSSVKTKN 72

  Fly    74 V----PAKSILTSM------QGRIANLLQSSKEPIIKQ---IINFHEMGIEITELLLKEPSVIEL 125
            |    |.:.::..|      .|.:.....:....:|.:   ::.|  .|.:..:::.::..:.:|
Worm    73 VIYIEPDEEVVEKMSKIDQFSGSLWTFDSTHPSAMIAKSNALVGF--FGTQCKKVMRQQKILDQL 135

  Fly   126 MKSNQTFDAVISEVFLNEAHFGFAEHFK----APLIGLGTFGAISWNTDLVGSPSPPSYVPSALL 186
            ...|  ||..|:|. ::...:...|:.|    ..::....|..:|   |::|.|..|||||....
Worm   136 RDEN--FDLAITEP-VDGCAYAIFEYLKIRDHVTVLSCVRFDHVS---DILGQPIAPSYVPGTQS 194

  Fly   187 KFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKN----------- 240
            .|:|||::.||:.|         |:.::|       .|..|.|.....|:|.|:
Worm   195 FFNDRMTMKERLLN---------FIQFYY-------GRFTFANILDQEYEMAKDILGIQRSWREV 243

  Fly   241 --TALVLLNQHVS-LSFPRPYSPNMIEVGGMHI--NRKRQPLPKDILEFIEGAEHGVIYFSMGSN 300
              .|..:.:.|:. |.||.|....:|.:||..:  |.|...:.|.....:...:..|: .|.|||
Worm   244 LPEASFIFSNHIPVLDFPSPTFDKIIPIGGFTVKTNEKSLKIDKKWDAILNIRKKNVL-ISFGSN 307

  Fly   301 LKSKTLPLEKRQALIDTFAQLKQRV-LWKFED--TDLPGKPANVFISDWFPQDDILAHDNVLAFI 362
            .|||.:|.|.::.|:..|:.:.... :||:||  .::.....|||||.|.||:::||...|..|:
Worm   308 AKSKDMPEEYKKTLLRVFSSMPDTTFIWKYEDPNVNIAKNLDNVFISSWLPQNELLADSRVTVFV 372

  Fly   363 THGGLLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLA-AIQKIINNP 426
            |||||.|..|.....||.:.||||.||..|....:::|....:...:||:..|:. .:..::..|
Worm   373 THGGLASVMELALMGKPAIMIPIFADQGRNAQMLKRHGGAAVLQKTDLSNFDLVRDTLNDVLTKP 437

  Fly   427 EATQRVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGI 491
            ......:.:::...:|.....|..|..||..:|......|.:..:..|.::|:.:|.:.|:...:
Worm   438 SYKLNAKKLAEMLNNQPTNAKEVLVKHVEFAARFGKLPMLDNYGRHQNIVEYYFIDILTIILSVL 502

  Fly   492 IFVLYCIFLLIRLVWRLLQELFIKKDTSKPKQ 523
            |.|.| ||:      |||:.:..:..::|.|:
Worm   503 ISVFY-IFV------RLLRFMLSRNRSTKDKR 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	100/372 (27%)
ugt-24	NP_500931.3	UDPGT	32..519	CDD:278624	135/518 (26%)
ugt-24	NP_500931.3	egt	<251..504	CDD:223071	71/253 (28%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	6	5.810