DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt-45

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_500410.2	Gene:	ugt-45 / 177139	WormBaseID:	WBGene00021372	Length:	527	Species:	Caenorhabditis elegans

Alignment Length:	541	Identity:	141/541 - (26%)
Similarity:	248/541 - (45%)	Gaps:	42/541 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LALLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFELKKP-----IKN 70
            |..||..:|...|.|..||.:.....||......||..|..|||.||.:.|.::..|     :..
Worm     4 LVFLLLFVLPAASCYKILVSVPKFGFSHMQTMGKLADILVEAGHDVTFLMPVDVPIPQNGTELAK 68

  Fly    71 IKDVPAKSILTSMQGR------IANL---LQSSKEPIIKQIINFHEMGIEITELLLKEPSVIELM 126
            :..||....:..:.|.      :|||   ..:||:.|:.......::....|:.|:...::::.|
Worm    69 VVLVPTTDAINEIMGHAMKSGAVANLWTHSANSKQGIMWSTDMIGQVSYHNTKNLIDNKALVQQM 133

  Fly   127 KSNQTFDAVISEVFLNEAHFGFAEHFKA----PLIGLGTFGAISWNTDLVGSPSPPSYVPSALLK 187
            | ::.||..|:|:|    .|.....|:.    .::|..|...........|:|..||:||::...
Worm   134 K-DEKFDIGITELF----DFSGLAFFEVIGLKNVMGAHTTSVFEGTLMATGAPILPSFVPASQTF 193

  Fly   188 FSDRMSLVERVGNQAFLTY-EYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTALVLLNQHVS 251
            ..|..|::.|: |..::|| .|.|.|......|:.|...|........:::..:.....:|....
Worm   194 TDDSGSILSRL-NNLYMTYWSYQFQNKIQSFAQKALDEHYEKGKAPKIWNLVSDITWFFVNSDPI 257

  Fly   252 LSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFIEGAEHGVIYFSMGSNLKSKTLPLEKRQALID 316
            ..||:|...|::|:.|:.: .:.:|:.|:..|.:......|: .|.||.....|:|...:::::|
Worm   258 FDFPKPLPQNIVEIAGISV-PEIKPVGKEWDEILSKRSKNVL-VSFGSIASPTTMPEAVKKSIVD 320

  Fly   317 TFAQLKQ-RVLWKFEDTD--LPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRK 378
            .||.... ..:||::||:  |.....||.|..|.||:|:||...:..|.||||:.|..||.....
Worm   321 AFAAFPDVTFIWKYDDTESKLTAHLDNVHIVKWMPQNDLLADKRISMFWTHGGMGSLMESAQKSV 385

  Fly   379 PFVGIPIFGDQFLNMARAEQNGYGVTVHYEEL---SSAKLLAAIQKIINNPEATQRVRDMSDRYR 440
            |.|.:||||||..|...|::  :||.:.|:::   ::.||:.|:::::.|||..:....::....
Worm   386 PLVVVPIFGDQMRNAQIAKR--HGVALIYDKMDLSNTKKLIGALKEVLENPEYKKSAELLARILA 448

  Fly   441 DQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCIFLLIRLV 505
            .::.:|.::.:..||...|........||.::.:|::|.|||.       :|..::..||.|...
Worm   449 TERFSPRQKIIDTVEMAGRFGQMPRWTSAGKEFSFLKYFNLDL-------VIIAVFIFFLSIVST 506

  Fly   506 WRLLQELFIKKDTSKPKQKAK 526
            ..|::.|..|...|..|:|::
Worm   507 VLLIRHLLAKLGFSGDKEKSE 527

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	93/359 (26%)
ugt-45	NP_500410.2	egt	14..513	CDD:223071	132/515 (26%)
ugt-45	NP_500410.2	UDPGT	19..510	CDD:278624	129/507 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14613
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810