DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt-52

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_499988.1	Gene:	ugt-52 / 176904	WormBaseID:	WBGene00018931	Length:	541	Species:	Caenorhabditis elegans

Alignment Length:	524	Identity:	107/524 - (20%)
Similarity:	214/524 - (40%)	Gaps:	68/524 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    13 LLLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISP---------------- 61
            :.||.|...:...:.|..:....:||.....:|.:.|...||.|.:|..
Worm    20 VFLFTLPRVIQTLHVLFYILLLGKSHIDFTDSLIESLVENGHTVDLIIARMNSHVKSNGTNMVTR 84

  Fly    62 -----FELKKPIKNIKDVPAKSILTSMQGRIANLLQSSKEPIIKQIINFHEMGIEITELLLKEPS 121
                 |:.:.|...     |..:|...:||         |....:...:.::..::.|:.|.:..
Worm    85 KYTYGFQEESPWNK-----APHLLNPFKGR---------ERTWNEHTYYMDIVTDLCEIGLSDAG 135

  Fly   122 VIELMKSNQTFDAVISEVFLNEAHFGFAEHFKAP-LIGLGTFGAISWNTDLVGSPSPPSYVPSAL 185
             :....|:|.:|..|:..:.| ......:::|.| ::.:.:...:...:...|.|:.|: |..|:
Worm   136 -LHAFISSQKYDIGIATEYEN-CGVALMKYYKIPSIVSVSSLPILDRQSLAAGMPNSPA-VTQAI 197

  Fly   186 LKFSDRMSLVERVGNQAFLTYEYI--FLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTALVLLNQ 248
            .:..|..:...:..|  ||.:.:|  .:|.:....|..:.:|:...| .|..::.::..|..:|.
Worm   198 FEAEDLTTYWGKFRN--FLNWAHITLIINPYCEKHQSEVIKKHLGEN-FDTSNLIESLDLAFVNS 259

  Fly   249 HVSLSFPRPYSPNMIEVGGMHINRKRQPLPKDILEFI--EGAEHGVIYFSMGSNLKSKTLPLEKR 311
            :..:..||..|..:..:||:::.:.:..|.:::.:.|  :...:|::.|..|:.:.|...|:|.|
Worm   260 NELIETPRVSSHKIKYIGGINLKKSKDRLDEEVEKVITQKPIGNGIVVFCFGTQVPSSLFPIEVR 324

  Fly   312 QALIDTFAQLKQ-RVLWKFE----DTDLPGKPANVFISDWFPQDDILAHDNVLAFITHGGLLSTT 371
            :|....|..... ..:||:|    |..:.....|:.:..|.||.|:|......|||:|.||.|..
Worm   325 RAFAQAFRHFPDFTFVWKYEMQDGDEQIFANTTNLRLLKWLPQTDLLNDARTKAFISHVGLNSYL 389

  Fly   372 ESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMS 436
            ||.|...|.:.:|:|.||..|.......|....:....|::..::..::.::.:...|...:.:|
Worm   390 ESSYAGVPILAVPLFADQPHNAFSGMSIGTTYMLDKTRLTTPNIVKGLEAVLYDSSYTLNAKRIS 454

  Fly   437 DRYRDQQQTPLERAVYWVEHVSR----HKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYC 497
            ....::...|.:..|.|:|..||    |:.   |....|:::..:|:.||          .:.:|
Worm   455 KMLHERPNPPKKIFVEWIEFASRNPLLHRN---LNLIGQNMSVFEYYCLD----------IISFC 506

  Fly   498 IFLL 501
            |.||
Worm   507 ILLL 510

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	78/362 (22%)
ugt-52	NP_499988.1	UDPGT	53..537	CDD:278624	100/491 (20%)
ugt-52	NP_499988.1	Glycosyltransferase_GTB_type	<231..517	CDD:299143	68/294 (23%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	3.810