DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt-25

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_491438.1	Gene:	ugt-25 / 172087	WormBaseID:	WBGene00015692	Length:	531	Species:	Caenorhabditis elegans

Alignment Length:	545	Identity:	137/545 - (25%)
Similarity:	251/545 - (46%)	Gaps:	61/545 - (11%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 LFCLLSC--VSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPF--ELKK---PIKNIK 72
            :|.|||.  |:|:|.||...:...||.:..:.||..|..|||.||.:.|.  |.:|   .:|..|
Worm     6 VFILLSVINVNAFNILVYSPSFGGSHTNFMARLADTLTEAGHNVTFVVPVADEARKGQLGVKKTK 70

  Fly    73 DVPAKSILTSMQGRIANLLQSSKEPIIKQIINFHEMGIEITE-----------LLLKEPSVIELM 126
            ||    ::....    .|::|..:|:...:..:.|..::.:.           :||   |....|
Worm    71 DV----VIVEQD----ELMKSEIKPLDDDMAQYWETDMDSSNADSIFSVFSDAMLL---SCNNFM 124

  Fly   127 KSNQTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWN--------------TDLVGSPSP 177
            ::.:.|:.      |...:|....:....:.|||...||..|              ...:|.|..
Worm   125 RNKKVFNE------LKSRNFDVGIYEPLSVCGLGYMHAIGINKLIMSSSCALYDGTVAAIGEPID 183

  Fly   178 PSYVPSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTA 242
            .||||.::.|..::|||.|::.|.. |:.....:.|....::..:|:|:..|:...:.|:..:::
Worm   184 FSYVPGSMSKSGEKMSLFEKLENYR-LSMASSRMQYGQWDKETEIYKKHLGNDIPHWRDLMPSSS 247

  Fly   243 LVLLNQHVSLSFPRPYSPNMIEVGGMHINR---KRQPLPKDILEFIEGAEHGVIYFSMGSNLKSK 304
            :...|....:.|||..:...:.:||:.::.   |.|.|..:....::...|.:: .|.||.::|.
Worm   248 VAFTNSIPYVDFPRSITQKTVPIGGISVDMEMIKSQKLSIEWSTVLDERPHNML-ISFGSMVRSM 311

  Fly   305 TLPLEKRQALIDTF-AQLKQRVLWKFEDTDLPGKPA--NVFISDWFPQDDILAHDNVLAFITHGG 366
            .:||:.|..|::.. ::.....:||:|:.:|.....  |::.|.|.||..:|....:.||:||||
Worm   312 DMPLKWRNGLLEAIKSEPNVTFIWKYENDNLEWAKGIQNIYFSKWVPQTALLNDARLTAFMTHGG 376

  Fly   367 LLSTTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSAKLL-AAIQKIINNPEATQ 430
            |.||.|..:..||.:.:|:|.||..|.....::|..:.||.:||.:.|.: ::|:.|::..:..:
Worm   377 LGSTNELAFLGKPALMVPVFADQDRNANMLARHGGVLVVHKKELGNFKTIKSSIRSILHEEKYQK 441

  Fly   431 RVRDMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLD---AMLILYGGII 492
            ..|.:|:...:|...|.|:.|.:.|.|::......:.|..:.|.|||.:.:|   |:.:.|..:|
Worm   442 NARKLSELLNNQPLKPKEQVVKYTEFVAKFGPFPQMDSYGRQLGFIQRNLIDIYAAISLSYLFVI 506

  Fly   493 FVLYCIFLLIRLVWRLLQELFIKKD 517
            .::|.:|..:.....|.....:|||
Worm   507 SLIYFVFKFVISKTPLKLVKLVKKD 531

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	91/369 (25%)
ugt-25	NP_491438.1	egt	1..477	CDD:223071	122/489 (25%)
ugt-25	NP_491438.1	UDPGT	29..530	CDD:278624	125/519 (24%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	5	4.810