DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Ugt302C1 and ugt-26

DIOPT Version :9

Sequence 1:	NP_652626.1	Gene:	Ugt302C1 / 53510	FlyBaseID:	FBgn0040259	Length:	528	Species:	Drosophila melanogaster
Sequence 2:	NP_491435.2	Gene:	ugt-26 / 172085	WormBaseID:	WBGene00015695	Length:	529	Species:	Caenorhabditis elegans

Alignment Length:	539	Identity:	143/539 - (26%)
Similarity:	240/539 - (44%)	Gaps:	55/539 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    14 LLFCLLSCVSAYNYLVVLHTAARSHYHVGSALAKGLAAAGHQVTIISPFEL-----KKPIKNIKD 73
            |:.|.||.||:.|.||.....|.||.:..:.||..|..|||.||.:.|..|     |..:|..||
Worm    11 LVLCTLSLVSSLNILVHSPAYAASHTNFMARLADTLTEAGHNVTFLVPIALEERRDKLGVKLTKD 75

  Fly    74 V-------PAKSILTSMQGRIANL--LQSSKEPIIKQIINFHEMGIEITELLLKEPSVIELMKSN 129
            |       ..||.|....|.|..|  ::.....|......::|:.|...|..::...|:..:||.
Worm    76 VIIVEQDEEMKSKLVPHSGSIEFLWIIEMDSSSIDAMFSWYNEIMILTCENFMRNKQVMSELKSR 140

  Fly   130 QTFDAVISEVFLNEAHFGFAEHFKAPLIGLGTFGAISWNTDL--------------VGSPSPPSY 180
            . ||..|:|.|              .:.|||.|..::....:              :|.|...|.
Worm   141 H-FDVAIAEPF--------------TICGLGLFEELNIKKTILVSSCAHYDFMLPHIGEPEDFSS 190

  Fly   181 VPSALLKFSDRMSLVERVGNQAFLTYEYIFLNYFYLPRQEVLYRKYFPNNKQDFYDMRKNTALVL 245
            ||:...|..:.||:.|:..|...:......|...: ..:..:||:.|.::..|:.::..:.:|..
Worm   191 VPTLSSKVGEEMSMTEKWENYRLVAETKASLAKLF-DAETRIYRESFGSDIPDWKELMSSASLYF 254

  Fly   246 LNQHVSLSFPRPYSPNMIEVGGMHIN---RKRQPLPKDILEFIEGAEHGVIYFSMGSNLKSKTLP 307
            .|.:..:.:||......|.:||:.::   .|.:.|.|:..|.:...:..:: .|.|||:.|..:|
Worm   255 TNSNPFIDYPRASIQKTISIGGITVDFQQIKSEKLNKEWEEVLNKRQKSML-ISFGSNVPSDKMP 318

  Fly   308 LEKRQALIDTFAQLKQ-RVLWKFEDTDLPGKP--ANVFISDWFPQDDILAHDNVLAFITHGGLLS 369
            ...:..:.:|...:.. ..:||:|..|:....  :|:..|.|.||..:|....:.||:|||||.|
Worm   319 AAWKAGIFETIKSMPNVTFIWKYESDDVSFADGISNIHFSKWVPQTALLNDPRLSAFLTHGGLGS 383

  Fly   370 TTESIYHRKPFVGIPIFGDQFLNMARAEQNGYGVTVHYEELSSA-KLLAAIQKIINNPEATQRVR 433
            |.|..|..||.|.:||:|||..|.....::|..:.:|.:||::. ::..|:..|:.|.:.|:...
Worm   384 TNELAYCAKPAVMVPIYGDQTRNANMLARHGSVIVLHKKELANVQRVKKAVHDILYNKQYTESAE 448

  Fly   434 DMSDRYRDQQQTPLERAVYWVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCI 498
            .:::..::|.:||.|..|.:.|.|:::.....:....:.|.:.|...||...:...|::.||...
Worm   449 RIAEMIKNQPKTPKETVVRYTEFVAKYGPFPQMAPHGRKLTYFQKTFLDIYSLFALGVVSVLTVA 513

  Fly   499 FLLIRLVWRLLQELFIKKD 517
            ||:||.|   |....:|||
Worm   514 FLVIRYV---LSCFKLKKD 529

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	egt	<117..466	CDD:223071	90/369 (24%)
ugt-26	NP_491435.2	egt	4..481	CDD:223071	127/486 (26%)
ugt-26	NP_491435.2	UDPGT	34..525	CDD:278624	130/510 (25%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	1	1.000	-	-		FOG0000004
OrthoInspector	1	1.000	-	-		otm14289
orthoMCL	1	0.900	-	-		OOG6_100052
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X13
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	7	6.810