Protein Alignment Ugt302C1 and UGT3A1

DIOPT Version :10

• Sequence 1: NP_652626.1
• Gene: Ugt302C1 / 53510
• FlyBaseID: FBgn0040259
• Length: 528
• Species: Drosophila melanogaster
• Sequence 2: XP_047272663.1
• Gene: UGT3A1 / 133688
• HGNCID: 26625
• Length: 526
• Species: Homo sapiens
• Alignment Length: 513
• Identity: 137/513 - (26%)
• Similarity: 232/513 - (45%)
• Gaps: 70/513 - (13%)

  Fly    37 SHYHVGSALAKGLAAAGHQVTII------------------------SPFELKKPIKNIKDVPAK 77
            |||.:...:::.|...||.||::                        ||.:.:|.||...|   .
Human    37 SHYLLLDRVSQILQEHGHNVTMLHQSGKFLIPDIKEEEKSYQVIRWFSPEDHQKRIKKHFD---S 98

  Fly    78 SILTSMQGRIANLLQSSKEPIIKQIINFHEMGIEITELLLKEPSVIELMKSNQTFDAVISEVFLN 142
            .|.|::.||      ...|.::|.:..|   |.:.:.||.:: .:::.:| |:.:|.|..|.| :
Human    99 YIETALDGR------KESEALVKLMEIF---GTQCSYLLSRK-DIMDSLK-NENYDLVFVEAF-D 151

  Fly   143 EAHFGFAEHFKAPLIGL--GTFGAISWNTDLVGSPSPPSYVPSALLKFSDRMSLVERVGNQAFLT 205
            ...|..||....|.:.:  .|||::.:     |.|||.||||......:|.|....||.|
Human   152 FCSFLIAEKLVKPFVAILPTTFGSLDF-----GLPSPLSYVPVFPSLLTDHMDFWGRVKN----- 206

  Fly   206 YEYIFLNYFYLPRQEVLYRKYFPNN-KQDFYD--------MRKNTALVLLNQHVSLSFPRPYSPN 261
                ||.:|...|.:...:..|.|. |:.|.:        :.....|..:|...:..|.||..||
Human   207 ----FLMFFSFSRSQWDMQSTFDNTIKEHFPEGSRPVLSHLLLKAELWFVNSDFAFDFARPLLPN 267

  Fly   262 MIEVGGMHINRKRQPLPKDILEFIEG-AEHGVIYFSMGSNLKSKTLPLEKRQALIDTFAQLKQRV 325
            .:.:||: :.:..:|:|:|:..||.. .:.|.:..:.||.|.:.. ..|..:.:.:.||.|.|.|
Human   268 TVYIGGL-MEKPIKPVPQDLDNFIANFGDAGFVLVAFGSMLNTHQ-SQEVLKKMHNAFAHLPQGV 330

  Fly   326 LWKFEDTDLPGK---PANVFISDWFPQDDILAHDNVLAFITHGGLLSTTESIYHRKPFVGIPIFG 387
            :|..:.:..|..   ..||.|.||.||.|:|||.::..|:||||..|..|:|.|..|.||:|:.|
Human   331 IWTCQSSHWPRDVHLATNVKIVDWLPQSDLLAHPSIRLFVTHGGQNSVMEAIRHGVPMVGLPVNG 395

  Fly   388 DQFLNMARAEQNGYGVTVHYEELSSAKLLAAIQKIINNPEATQRVRDMSDRYRDQQQTPLERAVY 452
            ||..||.|.....|||::...::::..|...::::|.:......|...|.....|..:|.:|.|.
Human   396 DQHGNMVRVVAKNYGVSIRLNQVTADTLTLTMKQVIEDKRYKSAVVAASVILHSQPLSPAQRLVG 460

  Fly   453 WVEHVSRHKGAKYLRSASQDLNFIQYHNLDAMLILYGGIIFVLYCIFLLIRLVWRLLQ 510
            |::|:.:..||.:|:..:....:.:.:.:|..:.|.|..:..::....|:.:|.|.|:
Human   461 WIDHILQTGGATHLKPYAFQQPWHEQYLIDVFVFLLGLTLGTMWLCGKLLGVVARWLR 518

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Ugt302C1	NP_652626.1	Glycosyltransferase_GTB-type	<185..507	CDD:471961	90/334 (27%)
UGT3A1	XP_047272663.1	Glycosyltransferase_GTB-type	36..526	CDD:471961	137/513 (27%)